&#945;-synuclein overexpression in the retina leads to vision impairment and degeneration of dopaminergic amacrine cells.

Marrocco, Elena; Indrieri, Alessia; Esposito, Federica; Tarallo, Valeria; Carboncino, Anna; Alvino, Filomena Grazia; De Falco, Sandro; Franco, Brunella; De Risi, Maria; De Leonibus, Elvira

α-synuclein overexpression in the retina leads to vision impairment and degeneration of dopaminergic amacrine cells.

Marrocco, Elena; Indrieri, Alessia; Esposito, Federica; Tarallo, Valeria; Carboncino, Anna; Alvino, Filomena Grazia; De Falco, Sandro; Franco, Brunella; De Risi, Maria; De Leonibus, Elvira.

Afiliación

Marrocco E; Telethon Institute of Genetics and Medicine, Telethon Foundation, Pozzuoli, Naples, Italy.
Indrieri A; Telethon Institute of Genetics and Medicine, Telethon Foundation, Pozzuoli, Naples, Italy.
Esposito F; Institute for Genetic and Biomedical Research (IRGB), National Research Council (CNR), Milan, Italy.
Tarallo V; Telethon Institute of Genetics and Medicine, Telethon Foundation, Pozzuoli, Naples, Italy.
Carboncino A; Institute of Genetics and Biophysics "Adriano Buzzati-Traverso", National Research Council (CNR), Naples, Italy.
Alvino FG; Institute of Genetics and Biophysics "Adriano Buzzati-Traverso", National Research Council (CNR), Naples, Italy.
De Falco S; Telethon Institute of Genetics and Medicine, Telethon Foundation, Pozzuoli, Naples, Italy.
Franco B; PhD program in Behavioral Neuroscience, Sapienza University of Rome, Rome, Italy.
De Risi M; Institute of Genetics and Biophysics "Adriano Buzzati-Traverso", National Research Council (CNR), Naples, Italy.
De Leonibus E; Telethon Institute of Genetics and Medicine, Telethon Foundation, Pozzuoli, Naples, Italy.

Sci Rep ; 10(1): 9619, 2020 06 15.

Article en En | MEDLINE | ID: mdl-32541823

Asunto(s)

Células Amacrinas/metabolismo; Neuronas Dopaminérgicas/metabolismo; Retina/metabolismo; Degeneración Retiniana/metabolismo; Trastornos de la Visión/metabolismo; alfa-Sinucleína/metabolismo; Células Amacrinas/patología; Animales; Neuronas Dopaminérgicas/patología; Femenino; Técnica del Anticuerpo Fluorescente; Levodopa/farmacología; Masculino; Ratones; Ratones Endogámicos C57BL; Retina/efectos de los fármacos; Retina/patología; Degeneración Retiniana/patología; Trastornos de la Visión/patología; Agudeza Visual

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Retina / Degeneración Retiniana / Trastornos de la Visión / Células Amacrinas / Alfa-Sinucleína / Neuronas Dopaminérgicas Límite: Animals Idioma: En Revista: Sci Rep Año: 2020 Tipo del documento: Article País de afiliación: Italia

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