Implementation of a Timed Barium Esophagram Protocol for Assessment of Esophageal Function in Children.
J Pediatr Gastroenterol Nutr
; 71(4): 470-475, 2020 10.
Article
en En
| MEDLINE
| ID: mdl-32639450
ABSTRACT
OBJECTIVES:
Timed barium esophagram (TBE) is a fluoroscopic study that is widely employed as an adjunctive tool for diagnosing esophageal emptying disorders in adults (eg, achalasia, esophagogastric junction outflow obstruction [EGJOO]) and for following response to treatment. We aimed to describe the characteristics and feasibility of a pediatric TBE protocol and provide a first report of the potential value of TBE for assessment of esophageal emptying in the pediatric population.METHODS:
Retrospective chart review of pediatric patients at a tertiary pediatric hospital who underwent TBE from October 2017 to October 2019. Patient and test characteristics were summarized using descriptive statistics. Results from patients who had both TBE and high-resolution esophageal manometry (HRM) were used to generate ROC curves for TBE to identify esophageal emptying disorders.RESULTS:
Twenty-two patients underwent 25 TBE. Fourteen of 23 (61%) received 150âmL barium volume per protocol. Nearly half (42%) of subjects could tolerate ingesting barium within 20âseconds. Nine individuals underwent HRM. The sensitivity of standard adult TBE criteria (1âcm barium column height at 5âminutes) to detect emptying disorder was 100%, specificity 40%. A modified diagnostic cutoff (1.6âcm height at 5âminutes) offered 100% sensitivity, 80% specificity.CONCLUSIONS:
TBE is feasible and should be considered an adjunctive noninvasive screen for impaired esophageal emptying in children. There was heterogeneous adherence to protocol for timing and volume of barium; however, studies remained interpretable. This population may benefit from different diagnostic cutoffs than adults, and clinical judgment should be used until specific diagnostic cutoffs are determined in children.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Acalasia del Esófago
Tipo de estudio:
Guideline
/
Observational_studies
/
Prognostic_studies
Límite:
Adult
/
Child
/
Humans
Idioma:
En
Revista:
J Pediatr Gastroenterol Nutr
Año:
2020
Tipo del documento:
Article