Utilization Phase Transition Component Method to Prepare Specially Functionalized Nanoemulsion by Adding Resveratrol/Phenethyl Resorcinol Mixed Active Components and Application in Free Radicals Removal.

To explore the possibility of using a specially functionalized nanoemulsion for the removal of free radical, resveratrol and phenethyl resorcinol were employed to form resveratrol/phenethyl resorcinol mixed active components, and the removal efficiency of free radicals was evaluated. Original nanoemulsion and specially functionalized-nanoemulsion were characterized by DLS and EPR. The free radical scavenging ability of the mixed active components of resveratrol/phenethyl resorcinol was determined as a function of the mass ratio of resveratrol to phenethyl resorcinol, temperature, and ionic strength. In the results, the removal of free radicals by the resveratrol/phenethyl resorcinol nanoemulsion system was found to be more effective than the nanoemulsion alone. At a higher resveratrol ratio, more than 68% of free radicals could be removed. The efficiency was also found to increase with rising temperature. However, efficiency decreased with the increase in ionic strength. In conclusion, compared with conventional nanoemulsion, the combined utilization of nanoemulsion and the mixed active components of resveratrol/phenethyl resorcinol achieved better results for the removal of free radicals because of synergistic effect between nanoemulsion droplets and the mixed active components of resveratrol/phenethyl resorcinol, involving hydrophobic binding, hydrogen binding, and partitioning.