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Clostridioides difficile Toxin A Remodels Membranes and Mediates DNA Entry Into Cells to Activate Toll-Like Receptor 9 Signaling.
Chen, Xinhua; Yang, Xiaotong; de Anda, Jaime; Huang, Jun; Li, Dan; Xu, Hua; Shields, Kelsey S; Dzunková, Mária; Hansen, Joshua; Patel, Ishan J; Yee, Eric U; Golenbock, Douglas T; Grant, Marianne A; Wong, Gerard C L; Kelly, Ciarán P.
Afiliación
  • Chen X; Division of Gastroenterology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts. Electronic address: xchen1@bidmc.harvard.edu.
  • Yang X; Division of Gastroenterology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts; Institute of Microbiology and Immunology, College of Life Sciences, Shanghai Normal University, Shanghai, China.
  • de Anda J; Department of Bioengineering, Department of Chemistry and Biochemistry, California Nano Systems Institute, University of California, Los Angeles, Los Angeles, California.
  • Huang J; Division of Gastroenterology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts; Department of Colorectal Surgery, The 6th Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
  • Li D; Division of Gastroenterology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
  • Xu H; Division of Gastroenterology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
  • Shields KS; Division of Gastroenterology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
  • Dzunková M; US Department of Energy Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, California.
  • Hansen J; Division of Gastroenterology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
  • Patel IJ; Stony Brook University Hospital, Stony Brook, New York.
  • Yee EU; Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas.
  • Golenbock DT; Division of Infectious Diseases and Immunology, University of Massachusetts Medical School, Worcester, Massachusetts.
  • Grant MA; Division of Molecular and Vascular Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
  • Wong GCL; Department of Bioengineering, Department of Chemistry and Biochemistry, California Nano Systems Institute, University of California, Los Angeles, Los Angeles, California. Electronic address: gclwong@seas.ucla.edu.
  • Kelly CP; Division of Gastroenterology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
Gastroenterology ; 159(6): 2181-2192.e1, 2020 12.
Article en En | MEDLINE | ID: mdl-32841647
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Toxinas Bacterianas / Clostridioides difficile / Infecciones por Clostridium / Colitis / Enterotoxinas / Receptor Toll-Like 9 Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Gastroenterology Año: 2020 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Toxinas Bacterianas / Clostridioides difficile / Infecciones por Clostridium / Colitis / Enterotoxinas / Receptor Toll-Like 9 Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Gastroenterology Año: 2020 Tipo del documento: Article