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A higher ctDNA fraction decreases survival in regorafenib-treated metastatic colorectal cancer patients. Results from the regorafenib's liquid biopsy translational biomarker phase II pilot study.
Unseld, Matthias; Belic, Jelena; Pierer, Kerstin; Zhou, Qing; Moser, Tina; Bauer, Raimund; Piringer, Gudrun; Gerger, Armin; Siebenhüner, Alexander; Speicher, Michael; Heitzer, Ellen; Prager, Gerald W.
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  • Unseld M; Department of Medicine I, Division of Palliative Medicine, Medical University of Vienna, Vienna, Austria.
  • Belic J; Institute of Human Genetics, Diagnostic and Research Center for Molecular BioMedicine, Medical University of Graz, Graz, Austria.
  • Pierer K; Institute of Human Genetics, Diagnostic and Research Center for Molecular BioMedicine, Medical University of Graz, Graz, Austria.
  • Zhou Q; Christian Doppler Laboratory for Liquid Biopsies for Early Detection of Cancer, Graz, Austria.
  • Moser T; Institute of Human Genetics, Diagnostic and Research Center for Molecular BioMedicine, Medical University of Graz, Graz, Austria.
  • Bauer R; Institute of Human Genetics, Diagnostic and Research Center for Molecular BioMedicine, Medical University of Graz, Graz, Austria.
  • Piringer G; Center for Pathobiochemistry and Genetics, Institute of Medical Chemistry, Medical University of Vienna, Vienna, Austria.
  • Gerger A; Klinikum Wels-Grieskirchen, Wels, Austria.
  • Siebenhüner A; Department of Internal Medicine, Division of Oncology, Medical University of Graz, Austria.
  • Speicher M; Clinic for Medical Oncology, University Hospital Zurich, Zurich, Switzerland.
  • Heitzer E; Institute of Human Genetics, Diagnostic and Research Center for Molecular BioMedicine, Medical University of Graz, Graz, Austria.
  • Prager GW; Institute of Human Genetics, Diagnostic and Research Center for Molecular BioMedicine, Medical University of Graz, Graz, Austria.
Int J Cancer ; 148(6): 1452-1461, 2021 03 15.
Article en En | MEDLINE | ID: mdl-32949150
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Compuestos de Fenilurea / Piridinas / Neoplasias Colorrectales / Biomarcadores de Tumor / ADN Tumoral Circulante Tipo de estudio: Clinical_trials / Observational_studies / Prognostic_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Int J Cancer Año: 2021 Tipo del documento: Article País de afiliación: Austria
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Compuestos de Fenilurea / Piridinas / Neoplasias Colorrectales / Biomarcadores de Tumor / ADN Tumoral Circulante Tipo de estudio: Clinical_trials / Observational_studies / Prognostic_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Int J Cancer Año: 2021 Tipo del documento: Article País de afiliación: Austria