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Ceramide analog [18F]F-HPA-12 detects sphingolipid disbalance in the brain of Alzheimer's disease transgenic mice by functioning as a metabolic probe.
Crivelli, Simone M; van Kruining, Daan; Luo, Qian; Stevens, Jo A A; Giovagnoni, Caterina; Paulus, Andreas; Bauwens, Matthias; Berkes, Dusan; de Vries, Helga E; Mulder, Monique T; Walter, Jochen; Waelkens, Etienne; Derua, Rita; Swinnen, Johannes V; Dehairs, Jonas; Mottaghy, Felix M; Losen, Mario; Bieberich, Erhard; Martinez-Martinez, Pilar.
Afiliación
  • Crivelli SM; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University, Universiteitssingel 50, 6229ER, Maastricht, The Netherlands.
  • van Kruining D; Department of Physiology, University of Kentucky College of Medicine, Lexington, KY, USA.
  • Luo Q; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University, Universiteitssingel 50, 6229ER, Maastricht, The Netherlands.
  • Stevens JAA; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University, Universiteitssingel 50, 6229ER, Maastricht, The Netherlands.
  • Giovagnoni C; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University, Universiteitssingel 50, 6229ER, Maastricht, The Netherlands.
  • Paulus A; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University, Universiteitssingel 50, 6229ER, Maastricht, The Netherlands.
  • Bauwens M; NUTRIM, School for Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, The Netherlands.
  • Berkes D; Department of Nuclear Medicine and Radiology, MUMC+, Maastricht, The Netherlands.
  • de Vries HE; Division of Nuclear Medicine, Uniklinikum Aachen, Aachen, Germany.
  • Mulder MT; NUTRIM, School for Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, The Netherlands.
  • Walter J; Department of Nuclear Medicine and Radiology, MUMC+, Maastricht, The Netherlands.
  • Waelkens E; Department of Organic Chemistry, Slovak University of Technology, Radlinského 9, 81237, Bratislava, Slovak Republic.
  • Derua R; Department of Molecular Cell Biology and Immunology, Amsterdam Neuroscience, Amsterdam UMC, Amsterdam, The Netherlands.
  • Swinnen JV; Department of Internal Medicine, Laboratory Vascular Medicine, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
  • Dehairs J; Department of Neurology, University Hospital Bonn, University of Bonn, Bonn, Germany.
  • Mottaghy FM; Laboratory of Protein Phosphorylation and Proteomics, KU Leuven, Leuven, Belgium.
  • Losen M; Laboratory of Protein Phosphorylation and Proteomics, KU Leuven, Leuven, Belgium.
  • Bieberich E; Laboratory of Lipid Metabolism and Cancer, KU Leuven, Leuven, Belgium.
  • Martinez-Martinez P; Laboratory of Lipid Metabolism and Cancer, KU Leuven, Leuven, Belgium.
Sci Rep ; 10(1): 19354, 2020 11 09.
Article en En | MEDLINE | ID: mdl-33168861
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Esfingolípidos / Encéfalo / Radioisótopos de Flúor / Ceramidas / Enfermedad de Alzheimer / Amidas Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Animals Idioma: En Revista: Sci Rep Año: 2020 Tipo del documento: Article País de afiliación: Países Bajos
Texto completo
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XML
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Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Esfingolípidos / Encéfalo / Radioisótopos de Flúor / Ceramidas / Enfermedad de Alzheimer / Amidas Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Animals Idioma: En Revista: Sci Rep Año: 2020 Tipo del documento: Article País de afiliación: Países Bajos