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Genome-edited, donor-derived allogeneic anti-CD19 chimeric antigen receptor T cells in paediatric and adult B-cell acute lymphoblastic leukaemia: results of two phase 1 studies.
Benjamin, Reuben; Graham, Charlotte; Yallop, Deborah; Jozwik, Agnieszka; Mirci-Danicar, Oana C; Lucchini, Giovanna; Pinner, Danielle; Jain, Nitin; Kantarjian, Hagop; Boissel, Nicolas; Maus, Marcela V; Frigault, Matthew J; Baruchel, André; Mohty, Mohamad; Gianella-Borradori, Athos; Binlich, Florence; Balandraud, Svetlana; Vitry, Fabien; Thomas, Elisabeth; Philippe, Anne; Fouliard, Sylvain; Dupouy, Sandra; Marchiq, Ibtissam; Almena-Carrasco, Maria; Ferry, Nicolas; Arnould, Sylvain; Konto, Cyril; Veys, Paul; Qasim, Waseem.
Afiliación
  • Benjamin R; Department of Haematological Medicine, King's College Hospital NHS Foundation Trust, London, UK; School of Cancer and Pharmaceutical Sciences, Kings College London, London, UK. Electronic address: reuben.benjamin@kcl.ac.uk.
  • Graham C; Department of Haematological Medicine, King's College Hospital NHS Foundation Trust, London, UK; School of Cancer and Pharmaceutical Sciences, Kings College London, London, UK.
  • Yallop D; Department of Haematological Medicine, King's College Hospital NHS Foundation Trust, London, UK.
  • Jozwik A; Department of Haematological Medicine, King's College Hospital NHS Foundation Trust, London, UK; School of Cancer and Pharmaceutical Sciences, Kings College London, London, UK.
  • Mirci-Danicar OC; Infection, Immunity & Inflammation Department, Great Ormond Street Hospital, London, UK.
  • Lucchini G; Infection, Immunity & Inflammation Department, Great Ormond Street Hospital, London, UK.
  • Pinner D; Infection, Immunity & Inflammation Department, Great Ormond Street Hospital, London, UK.
  • Jain N; The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Kantarjian H; The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Boissel N; Department of Hematology, Hôpital Saint Louis, Paris, France.
  • Maus MV; Division of Hematology and Oncology, Massachusetts General Hospital, Boston, MA, USA.
  • Frigault MJ; Division of Hematology and Oncology, Massachusetts General Hospital, Boston, MA, USA.
  • Baruchel A; Department of Pediatric Hematology, K Hôpital Universitaire Robert Debré, Paris, France.
  • Mohty M; INSERM UMRS 938, Sorbonne University, Saint-Antoine Hospital, Paris, France.
  • Gianella-Borradori A; Institut de Recherches Internationales Servier, Suresnes, France.
  • Binlich F; Institut de Recherches Internationales Servier, Suresnes, France.
  • Balandraud S; Institut de Recherches Internationales Servier, Suresnes, France.
  • Vitry F; Institut de Recherches Internationales Servier, Suresnes, France; Laboratoires Davolterra, Paris, France.
  • Thomas E; Institut de Recherches Internationales Servier, Suresnes, France.
  • Philippe A; Institut de Recherches Internationales Servier, Suresnes, France; Pfizer, Paris, France.
  • Fouliard S; Institut de Recherches Internationales Servier, Suresnes, France.
  • Dupouy S; Institut de Recherches Internationales Servier, Suresnes, France.
  • Marchiq I; Institut de Recherches Servier, Croissy sur seine, France.
  • Almena-Carrasco M; Institut de Recherches Internationales Servier, Suresnes, France.
  • Ferry N; Institut de Recherches Internationales Servier, Suresnes, France.
  • Arnould S; Les Laboratoires Servier, Suresnes, France.
  • Konto C; Allogene Therapeutics, South San Francisco, CA, USA.
  • Veys P; Infection, Immunity & Inflammation Department, Great Ormond Street Hospital, London, UK.
  • Qasim W; Infection, Immunity & Inflammation Department, Great Ormond Street Hospital, London, UK.
Lancet ; 396(10266): 1885-1894, 2020 12 12.
Article en En | MEDLINE | ID: mdl-33308471
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Antígenos CD19 / Leucemia-Linfoma Linfoblástico de Células Precursoras / Receptores Quiméricos de Antígenos Tipo de estudio: Clinical_trials / Etiology_studies Límite: Adult / Child, preschool / Female / Humans / Male Idioma: En Revista: Lancet Año: 2020 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Antígenos CD19 / Leucemia-Linfoma Linfoblástico de Células Precursoras / Receptores Quiméricos de Antígenos Tipo de estudio: Clinical_trials / Etiology_studies Límite: Adult / Child, preschool / Female / Humans / Male Idioma: En Revista: Lancet Año: 2020 Tipo del documento: Article