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Human neutralizing antibodies against SARS-CoV-2 require intact Fc effector functions for optimal therapeutic protection.
Winkler, Emma S; Gilchuk, Pavlo; Yu, Jinsheng; Bailey, Adam L; Chen, Rita E; Chong, Zhenlu; Zost, Seth J; Jang, Hyesun; Huang, Ying; Allen, James D; Case, James Brett; Sutton, Rachel E; Carnahan, Robert H; Darling, Tamarand L; Boon, Adrianus C M; Mack, Matthias; Head, Richard D; Ross, Ted M; Crowe, James E; Diamond, Michael S.
Afiliación
  • Winkler ES; Department of Medicine, Washington University School of Medicine, St. Louis, St. Louis, MO 63110, USA; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, St. Louis, MO 63110, USA.
  • Gilchuk P; Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
  • Yu J; Department of Genetics, Washington University School of Medicine, St. Louis, St. Louis, MO 63110, USA.
  • Bailey AL; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, St. Louis, MO 63110, USA.
  • Chen RE; Department of Medicine, Washington University School of Medicine, St. Louis, St. Louis, MO 63110, USA; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, St. Louis, MO 63110, USA.
  • Chong Z; Department of Medicine, Washington University School of Medicine, St. Louis, St. Louis, MO 63110, USA.
  • Zost SJ; Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
  • Jang H; Center for Vaccines and Immunology, University of Georgia, Athens, GA 30605, USA.
  • Huang Y; Center for Vaccines and Immunology, University of Georgia, Athens, GA 30605, USA.
  • Allen JD; Center for Vaccines and Immunology, University of Georgia, Athens, GA 30605, USA.
  • Case JB; Department of Medicine, Washington University School of Medicine, St. Louis, St. Louis, MO 63110, USA.
  • Sutton RE; Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
  • Carnahan RH; Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
  • Darling TL; Department of Medicine, Washington University School of Medicine, St. Louis, St. Louis, MO 63110, USA.
  • Boon ACM; Department of Medicine, Washington University School of Medicine, St. Louis, St. Louis, MO 63110, USA; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, St. Louis, MO 63110, USA; Department of Molecular Microbiology, Washington University School of Medicine
  • Mack M; Department of Internal Medicine II, University Hospital Regensburg, 93053 Regensburg, Germany.
  • Head RD; Department of Genetics, Washington University School of Medicine, St. Louis, St. Louis, MO 63110, USA.
  • Ross TM; Center for Vaccines and Immunology, University of Georgia, Athens, GA 30605, USA.
  • Crowe JE; Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
  • Diamond MS; Department of Medicine, Washington University School of Medicine, St. Louis, St. Louis, MO 63110, USA; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, St. Louis, MO 63110, USA; Department of Molecular Microbiology, Washington University School of Medicine
Cell ; 184(7): 1804-1820.e16, 2021 04 01.
Article en En | MEDLINE | ID: mdl-33691139

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Fragmentos Fc de Inmunoglobulinas / Linfocitos T CD8-positivos / Anticuerpos Neutralizantes / COVID-19 / Anticuerpos Monoclonales / Anticuerpos Antivirales Límite: Animals / Female / Humans / Male Idioma: En Revista: Cell Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Fragmentos Fc de Inmunoglobulinas / Linfocitos T CD8-positivos / Anticuerpos Neutralizantes / COVID-19 / Anticuerpos Monoclonales / Anticuerpos Antivirales Límite: Animals / Female / Humans / Male Idioma: En Revista: Cell Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos