Cannabis Abuse and Perioperative Complications Following Inpatient Spine Surgery in the United States.
Spine (Phila Pa 1976)
; 46(11): 734-743, 2021 Jun 01.
Article
en En
| MEDLINE
| ID: mdl-33769411
Retrospective cohort analysis of a nationwide administrative database. The aim of this study was to analyze the association between cannabis abuse and serious adverse events following elective spine surgery. Cannabis is the most popular illicit drug in the United States, and its use has been increasing in light of state efforts to decriminalize and legalize its use for both medical and recreational purposes. Its legal status has long precluded extensive research into its adverse effects, and to date, little research has been done on the sequelae of cannabis on surgical patients, particularly in spine surgery. The 20122015 Nationwide Inpatient Sample was queried for all patients undergoing common elective spine surgery procedures. These patients were then grouped by the presence of concurrent diagnosis of cannabis use disorder and compared with respect to various peri- and postoperative complications, all-cause mortality, discharge disposition, length of stay, and hospitalization costs. Propensity score matching was utilized to control for potential baseline confounders. A total of 423,978 patients met inclusion/exclusion criteria, 2393 (0.56%) of whom had cannabis use disorder. After controlling for baseline characteristics and comorbid tobacco use, these patients similar inpatient mortality, but higher rates of perioperative thromboembolism (odds ratio [OR] 2.2; 95% confidence interval [CI] 1.24.0; P â=â0.005), respiratory complications (OR 2.0; 95% CI 1.42.9; P â<â0.001), neurologic complications such as stroke and anoxic brain injury (OR 2.9; 95% CI 1.27.5; P â=â0.007), septicemia/sepsis (OR 1.5; 95% CI 1.0 to 2.5; P â=â0.031), and nonroutine discharge ( P â<â0.001), as well as increased lengths of stay (7.1 vs. 5.2âdays, P â<â0.001) and hospitalization charges ($137,631.30 vs. $116,112.60, P â<â0.001). Cannabis abuse appears to be associated with increased perioperative morbidity among spine surgery patients. Physicians should ensure that a thorough preoperative drug use history is taken, and that affected patients be adequately informed of associated risks. Level of Evidence: 3.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Complicaciones Posoperatorias
/
Enfermedades de la Columna Vertebral
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Abuso de Marihuana
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Procedimientos Ortopédicos
/
Complicaciones Intraoperatorias
Tipo de estudio:
Observational_studies
Límite:
Humans
País/Región como asunto:
America do norte
Idioma:
En
Revista:
Spine (Phila Pa 1976)
Año:
2021
Tipo del documento:
Article
País de afiliación:
Israel