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Metformin impairs cisplatin resistance effects in A549 lung cancer cells through mTOR signaling and other metabolic pathways.
Morelli, Ana Paula; Tortelli, Tharcísio Citrângulo; Pavan, Isadora Carolina Betim; Silva, Fernando Riback; Granato, Daniela Campos; Peruca, Guilherme Francisco; Pauletti, Bianca Alves; Domingues, Romênia Ramos; Bezerra, Rosangela Maria Neves; De Moura, Leandro Pereira; Paes Leme, Adriana Franco; Chammas, Roger; Simabuco, Fernando Moreira.
Afiliación
  • Morelli AP; Multidisciplinary Laboratory of Food and Health, School of Applied Sciences, State University of Campinas, Limeira, SP 13484­350, Brazil.
  • Tortelli TC; Centro de Investigação Translacional em Oncologia, Departamento de Radiologia e Oncologia, Faculdade de Medicina da Universidade de São Paulo and Instituto do Câncer do Estado de São Paulo, São Paulo, SP 04021­001, Brazil.
  • Pavan ICB; Multidisciplinary Laboratory of Food and Health, School of Applied Sciences, State University of Campinas, Limeira, SP 13484­350, Brazil.
  • Silva FR; Laboratory of Signaling Mechanisms, School of Pharmaceutical Sciences, State University of Campinas, Campinas, SP 13083­871, Brazil.
  • Granato DC; Brazilian Biosciences National Laboratory, Brazilian Center for Research in Energy and Materials, Campinas, SP 13083­970, Brazil.
  • Peruca GF; Exercise Cell Biology Laboratory, School of Applied Sciences, State University of Campinas, Limeira, SP 13484­350, Brazil.
  • Pauletti BA; Brazilian Biosciences National Laboratory, Brazilian Center for Research in Energy and Materials, Campinas, SP 13083­970, Brazil.
  • Domingues RR; Brazilian Biosciences National Laboratory, Brazilian Center for Research in Energy and Materials, Campinas, SP 13083­970, Brazil.
  • Bezerra RMN; Multidisciplinary Laboratory of Food and Health, School of Applied Sciences, State University of Campinas, Limeira, SP 13484­350, Brazil.
  • De Moura LP; Exercise Cell Biology Laboratory, School of Applied Sciences, State University of Campinas, Limeira, SP 13484­350, Brazil.
  • Paes Leme AF; Brazilian Biosciences National Laboratory, Brazilian Center for Research in Energy and Materials, Campinas, SP 13083­970, Brazil.
  • Chammas R; Centro de Investigação Translacional em Oncologia, Departamento de Radiologia e Oncologia, Faculdade de Medicina da Universidade de São Paulo and Instituto do Câncer do Estado de São Paulo, São Paulo, SP 04021­001, Brazil.
  • Simabuco FM; Multidisciplinary Laboratory of Food and Health, School of Applied Sciences, State University of Campinas, Limeira, SP 13484­350, Brazil.
Int J Oncol ; 58(6)2021 06.
Article en En | MEDLINE | ID: mdl-33846781
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Protocolos de Quimioterapia Combinada Antineoplásica / Cisplatino / Carcinoma de Pulmón de Células no Pequeñas / Resistencia a Antineoplásicos / Neoplasias Pulmonares / Metformina Límite: Humans Idioma: En Revista: Int J Oncol Asunto de la revista: NEOPLASIAS Año: 2021 Tipo del documento: Article País de afiliación: Brasil
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Protocolos de Quimioterapia Combinada Antineoplásica / Cisplatino / Carcinoma de Pulmón de Células no Pequeñas / Resistencia a Antineoplásicos / Neoplasias Pulmonares / Metformina Límite: Humans Idioma: En Revista: Int J Oncol Asunto de la revista: NEOPLASIAS Año: 2021 Tipo del documento: Article País de afiliación: Brasil