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Recurrent deletions in clonal hematopoiesis are driven by microhomology-mediated end joining.
Feldman, Tzah; Bercovich, Akhiad; Moskovitz, Yoni; Chapal-Ilani, Noa; Mitchell, Amanda; Medeiros, Jessie J F; Biezuner, Tamir; Kaushansky, Nathali; Minden, Mark D; Gupta, Vikas; Milyavsky, Michael; Livneh, Zvi; Tanay, Amos; Shlush, Liran I.
Afiliación
  • Feldman T; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.
  • Bercovich A; Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot, Israel.
  • Moskovitz Y; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.
  • Chapal-Ilani N; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.
  • Mitchell A; Princess Margaret Cancer Centre, University Health Network (UHN), Toronto, ON, Canada.
  • Medeiros JJF; Princess Margaret Cancer Centre, University Health Network (UHN), Toronto, ON, Canada.
  • Biezuner T; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.
  • Kaushansky N; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.
  • Minden MD; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.
  • Gupta V; Princess Margaret Cancer Centre, University Health Network (UHN), Toronto, ON, Canada.
  • Milyavsky M; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.
  • Livneh Z; Department of Medicine, University of Toronto, Toronto, ON, Canada.
  • Tanay A; Division of Medical Oncology and Hematology, University Health Network, Toronto, ON, Canada.
  • Shlush LI; Princess Margaret Cancer Centre, University Health Network (UHN), Toronto, ON, Canada.
Nat Commun ; 12(1): 2455, 2021 04 28.
Article en En | MEDLINE | ID: mdl-33911081

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Leucemia Mieloide / ADN Polimerasa Dirigida por ADN / Reparación del ADN por Unión de Extremidades / Poli(ADP-Ribosa) Polimerasa-1 / Hematopoyesis Clonal Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article País de afiliación: Israel

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Leucemia Mieloide / ADN Polimerasa Dirigida por ADN / Reparación del ADN por Unión de Extremidades / Poli(ADP-Ribosa) Polimerasa-1 / Hematopoyesis Clonal Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article País de afiliación: Israel