Innate-like Gene Expression of Lung-Resident Memory CD8<sup>+</sup> T Cells during Experimental Human Influenza: A Clinical Study.

Paterson, Suzanna; Kar, Satwik; Ung, Seng Kuong; Gardener, Zoe; Bergstrom, Emma; Ascough, Stephanie; Kalyan, Mohini; Zyla, Joanna; Maertzdorf, Jeroen; Mollenkopf, Hans-Joachim; Weiner, January; Jozwik, Agnieszka; Jarvis, Hannah; Jha, Akhilesh; Nicholson, Bradly P; Veldman, Timothy; Woods, Chris W; Mallia, Patrick; Kon, Onn Min; Kaufmann, Stefan H E; Openshaw, Peter J; Chiu, Christopher

Innate-like Gene Expression of Lung-Resident Memory CD8⁺ T Cells during Experimental Human Influenza: A Clinical Study.

Paterson, Suzanna; Kar, Satwik; Ung, Seng Kuong; Gardener, Zoe; Bergstrom, Emma; Ascough, Stephanie; Kalyan, Mohini; Zyla, Joanna; Maertzdorf, Jeroen; Mollenkopf, Hans-Joachim; Weiner, January; Jozwik, Agnieszka; Jarvis, Hannah; Jha, Akhilesh; Nicholson, Bradly P; Veldman, Timothy; Woods, Chris W; Mallia, Patrick; Kon, Onn Min; Kaufmann, Stefan H E; Openshaw, Peter J; Chiu, Christopher.

Afiliación

Paterson S; Department of Infectious Disease, Hammersmith Campus, and.
Kar S; Department of Infectious Disease, Hammersmith Campus, and.
Ung SK; Department of Infectious Disease, Hammersmith Campus, and.
Gardener Z; Department of Infectious Disease, Hammersmith Campus, and.
Bergstrom E; Department of Infectious Disease, Hammersmith Campus, and.
Ascough S; Department of Infectious Disease, Hammersmith Campus, and.
Kalyan M; Department of Infectious Disease, Hammersmith Campus, and.
Zyla J; Department of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany.
Maertzdorf J; Department of Data Science and Engineering, Silesian University of Technology, Gliwice, Poland.
Mollenkopf HJ; Department of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany.
Weiner J; Department of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany.
Jozwik A; Department of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany.
Jarvis H; National Heart and Lung Institute, St. Mary's Campus, Imperial College London, London, United Kingdom.
Jha A; National Heart and Lung Institute, St. Mary's Campus, Imperial College London, London, United Kingdom.
Nicholson BP; National Heart and Lung Institute, St. Mary's Campus, Imperial College London, London, United Kingdom.
Veldman T; Institute for Medical Research, Durham Veterans Affairs Medical Center, Durham, North Carolina; and.
Woods CW; Center for Applied Genomics and Precision Medicine, Department of Medicine, Duke University, Durham, North Carolina.
Mallia P; Center for Applied Genomics and Precision Medicine, Department of Medicine, Duke University, Durham, North Carolina.
Kon OM; National Heart and Lung Institute, St. Mary's Campus, Imperial College London, London, United Kingdom.
Kaufmann SHE; National Heart and Lung Institute, St. Mary's Campus, Imperial College London, London, United Kingdom.
Openshaw PJ; Department of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany.
Chiu C; National Heart and Lung Institute, St. Mary's Campus, Imperial College London, London, United Kingdom.

Am J Respir Crit Care Med ; 204(7): 826-841, 2021 10 01.

Article en En | MEDLINE | ID: mdl-34256007

Asunto(s)

Linfocitos T CD8-positivos/inmunología; Inmunidad Innata/genética; Subtipo H1N1 del Virus de la Influenza A/inmunología; Gripe Humana/inmunología; Inmunidad Adaptativa/genética; Adolescente; Adulto; Antígenos CD/genética; Antígenos CD/metabolismo; Antígenos de Diferenciación de Linfocitos T/genética; Antígenos de Diferenciación de Linfocitos T/metabolismo; Biomarcadores/metabolismo; Líquido del Lavado Bronquioalveolar/inmunología; Líquido del Lavado Bronquioalveolar/virología; Linfocitos T CD8-positivos/metabolismo; Quimiocinas/metabolismo; Femenino; Expresión Génica; Perfilación de la Expresión Génica; Voluntarios Sanos; Humanos; Gripe Humana/genética; Gripe Humana/virología; Cadenas alfa de Integrinas/genética; Cadenas alfa de Integrinas/metabolismo; Cinética; Lectinas Tipo C/genética; Lectinas Tipo C/metabolismo; Masculino; Persona de Mediana Edad; Fenotipo; Sistema Respiratorio/inmunología; Sistema Respiratorio/virología; Carga Viral; Adulto Joven

Palabras clave

CD8+ T cell; controlled human infection; influenza; resident memory

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Linfocitos T CD8-positivos / Gripe Humana / Subtipo H1N1 del Virus de la Influenza A / Inmunidad Innata Idioma: En Revista: Am J Respir Crit Care Med Asunto de la revista: TERAPIA INTENSIVA Año: 2021 Tipo del documento: Article

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