Adeno-Associated Vector-Delivered CRISPR/<i>Sa</i>Cas9 System Reduces Feline Leukemia Virus Production In Vitro.

Helfer-Hungerbuehler, A Katrin; Shah, Jimit; Meili, Theres; Boenzli, Eva; Li, Pengfei; Hofmann-Lehmann, Regina

Adeno-Associated Vector-Delivered CRISPR/SaCas9 System Reduces Feline Leukemia Virus Production In Vitro.

Helfer-Hungerbuehler, A Katrin; Shah, Jimit; Meili, Theres; Boenzli, Eva; Li, Pengfei; Hofmann-Lehmann, Regina.

Afiliación

Helfer-Hungerbuehler AK; Clinical Laboratory, Center for Clinical Studies, Department of Clinical Diagnostics and Services, Vetsuisse Faculty, University of Zurich, 8057 Zurich, Switzerland.
Shah J; Clinical Laboratory, Center for Clinical Studies, Department of Clinical Diagnostics and Services, Vetsuisse Faculty, University of Zurich, 8057 Zurich, Switzerland.
Meili T; Clinical Laboratory, Center for Clinical Studies, Department of Clinical Diagnostics and Services, Vetsuisse Faculty, University of Zurich, 8057 Zurich, Switzerland.
Boenzli E; Clinical Laboratory, Center for Clinical Studies, Department of Clinical Diagnostics and Services, Vetsuisse Faculty, University of Zurich, 8057 Zurich, Switzerland.
Li P; Clinical Laboratory, Center for Clinical Studies, Department of Clinical Diagnostics and Services, Vetsuisse Faculty, University of Zurich, 8057 Zurich, Switzerland.
Hofmann-Lehmann R; Clinical Laboratory, Center for Clinical Studies, Department of Clinical Diagnostics and Services, Vetsuisse Faculty, University of Zurich, 8057 Zurich, Switzerland.

Viruses ; 13(8)2021 08 18.

Article en En | MEDLINE | ID: mdl-34452500

Asunto(s)

Dependovirus/genética; Terapia Genética; Vectores Genéticos/genética; Virus de la Leucemia Felina/fisiología; Leucemia Felina/terapia; Leucemia Felina/virología; Replicación Viral; Animales; Sistemas CRISPR-Cas; Gatos; Repeticiones Palindrómicas Cortas Agrupadas y Regularmente Espaciadas; Dependovirus/metabolismo; Edición Génica; Vectores Genéticos/metabolismo; Virus de la Leucemia Felina/genética; Leucemia Felina/genética; Carga Viral

Palabras clave

AAV; CRISPR; FeLV; SaCas9; cat; feline leukemia virus; gene editing; provirus

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Replicación Viral / Terapia Genética / Leucemia Felina / Dependovirus / Virus de la Leucemia Felina / Vectores Genéticos Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals Idioma: En Revista: Viruses Año: 2021 Tipo del documento: Article País de afiliación: Suiza

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