Sigma-1 Receptor Agonists Acting on Aquaporin-Mediated H<sub>2</sub>O<sub>2</sub> Permeability: New Tools for Counteracting Oxidative Stress.

Pellavio, Giorgia; Rossino, Giacomo; Gastaldi, Giulia; Rossi, Daniela; Linciano, Pasquale; Collina, Simona; Laforenza, Umberto

Sigma-1 Receptor Agonists Acting on Aquaporin-Mediated H₂O₂ Permeability: New Tools for Counteracting Oxidative Stress.

Pellavio, Giorgia; Rossino, Giacomo; Gastaldi, Giulia; Rossi, Daniela; Linciano, Pasquale; Collina, Simona; Laforenza, Umberto.

Afiliación

Pellavio G; Department of Molecular Medicine, Human Physiology Unit, University of Pavia, I-27100 Pavia, Italy.
Rossino G; Department of Drug Sciences, Medicinal Chemistry and Pharmaceutical Technology Section, University of Pavia, I-27100 Pavia, Italy.
Gastaldi G; Department of Molecular Medicine, Human Physiology Unit, University of Pavia, I-27100 Pavia, Italy.
Rossi D; Centre for Health Technology (CHT), University of Pavia, I-27100 Pavia, Italy.
Linciano P; Department of Drug Sciences, Medicinal Chemistry and Pharmaceutical Technology Section, University of Pavia, I-27100 Pavia, Italy.
Collina S; Department of Drug Sciences, Medicinal Chemistry and Pharmaceutical Technology Section, University of Pavia, I-27100 Pavia, Italy.
Laforenza U; Department of Drug Sciences, Medicinal Chemistry and Pharmaceutical Technology Section, University of Pavia, I-27100 Pavia, Italy.

Int J Mol Sci ; 22(18)2021 Sep 10.

Article en En | MEDLINE | ID: mdl-34575952

Asunto(s)

Acuaporinas/metabolismo; Peróxido de Hidrógeno/metabolismo; Estrés Oxidativo/efectos de los fármacos; Receptores sigma/genética; Acuaporinas/genética; Estrés del Retículo Endoplásmico/efectos de los fármacos; Células HeLa; Humanos; Permeabilidad/efectos de los fármacos; Peroxirredoxinas/genética; Peroxirredoxinas/metabolismo; Especies Reactivas de Oxígeno/metabolismo; Receptores sigma/agonistas; Receptores sigma/metabolismo; Receptor Sigma-1

Palabras clave

Sigma1 receptor modulators; Sigma1 receptors; hydrogen peroxide; neurodegenerative diseases; oxidative stress; peroxiporins; water channels

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Receptores sigma / Estrés Oxidativo / Acuaporinas / Peróxido de Hidrógeno Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Int J Mol Sci Año: 2021 Tipo del documento: Article País de afiliación: Italia

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