Oral desensitization in egg acute food protein-induced enterocolitis syndrome.
Eur Rev Med Pharmacol Sci
; 25(18): 5766-5768, 2021 Sep.
Article
en En
| MEDLINE
| ID: mdl-34604967
ABSTRACT
OBJECTIVE:
Strict avoidance of trigger food is the primary management of food protein-induced enterocolitis syndrome (FPIES). No published data are available on active induction of tolerance with oral desensitization (OD) in FPIES. CASE REPORT We carried out an OD in a 9 and a half years old boy with persistent acute egg FPIES. OD was performed with increasing doses of raw egg every week, starting with an initial dose of 0.2 ml. The boy presented mild and transient gastrointestinal adverse reactions when the 4 ml dose was reached. He could tolerate a whole raw egg in less than 14 months.CONCLUSIONS:
Even though randomized controlled clinical trials on patients including various phenotypes of FPIES are needed, our experience is encouraging about the possible efficacy and safety of OD in this food allergy.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Desensibilización Inmunológica
/
Hipersensibilidad al Huevo
/
Ingestión de Alimentos
/
Huevos
/
Enterocolitis
Tipo de estudio:
Clinical_trials
Límite:
Humans
/
Infant
/
Male
Idioma:
En
Revista:
Eur Rev Med Pharmacol Sci
Asunto de la revista:
FARMACOLOGIA
/
TOXICOLOGIA
Año:
2021
Tipo del documento:
Article