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Pharmacological characterization of GLPG1972/S201086, a potent and selective small-molecule inhibitor of ADAMTS5.
Clement-Lacroix, P; Little, C B; Smith, M M; Cottereaux, C; Merciris, D; Meurisse, S; Mollat, P; Touitou, R; Brebion, F; Gosmini, R; De Ceuninck, F; Botez, I; Lepescheux, L; van der Aar, E; Christophe, T; Vandervoort, N; Blanqué, R; Comas, D; Deprez, P; Amantini, D.
Afiliación
  • Clement-Lacroix P; Galapagos SASU, Romainville, France. Electronic address: Philippe.Clement-Lacroix@glpg.com.
  • Little CB; Raymond Purves Bone and Joint Research Laboratories, University of Sydney, Kolling Institute, Northern Sydney Local Health District, Royal North Shore Hospital, St Leonards, NSW, Australia. Electronic address: christopher.little@sydney.edu.au.
  • Smith MM; Raymond Purves Bone and Joint Research Laboratories, University of Sydney, Kolling Institute, Northern Sydney Local Health District, Royal North Shore Hospital, St Leonards, NSW, Australia. Electronic address: mobsmith@sydney.edu.au.
  • Cottereaux C; Galapagos SASU, Romainville, France. Electronic address: Celine.Cottereaux@glpg.com.
  • Merciris D; Galapagos SASU, Romainville, France. Electronic address: Didier.MERCIRIS@glpg.com.
  • Meurisse S; Galapagos SASU, Romainville, France. Electronic address: Sandrine.Meurisse@glpg.com.
  • Mollat P; Galapagos SASU, Romainville, France. Electronic address: Patrick.Mollat@glpg.com.
  • Touitou R; Galapagos SASU, Romainville, France. Electronic address: Robert.Touitou@glpg.com.
  • Brebion F; Galapagos SASU, Romainville, France. Electronic address: Franck.Brebion@glpg.com.
  • Gosmini R; Galapagos SASU, Romainville, France. Electronic address: Romain.Gosmini@glpg.com.
  • De Ceuninck F; Institut de Recherches Servier, France. Electronic address: frederic.deceuninck@servier.com.
  • Botez I; Institut de Recherches Servier, France. Electronic address: iuliana.botez@servier.com.
  • Lepescheux L; Galapagos SASU, Romainville, France. Electronic address: Lien.Lepescheux@glpg.com.
  • van der Aar E; Galapagos NV, Mechelen, Belgium. Electronic address: Ellen.vanderAar@glpg.com.
  • Christophe T; Galapagos NV, Mechelen, Belgium. Electronic address: Thierry.Christophe@glpg.com.
  • Vandervoort N; Galapagos NV, Mechelen, Belgium. Electronic address: nele.vandervoort@glpg.com.
  • Blanqué R; Galapagos SASU, Romainville, France. Electronic address: Roland.Blanque@glpg.com.
  • Comas D; Galapagos SASU, Romainville, France. Electronic address: Daniel.Comas@glpg.com.
  • Deprez P; Galapagos SASU, Romainville, France. Electronic address: Pierre.Deprez@glpg.com.
  • Amantini D; Galapagos SASU, Romainville, France. Electronic address: David.Amantini@glpg.com.
Osteoarthritis Cartilage ; 30(2): 291-301, 2022 02.
Article en En | MEDLINE | ID: mdl-34626798
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Piperazinas / Proteína ADAMTS5 Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Osteoarthritis Cartilage Asunto de la revista: ORTOPEDIA / REUMATOLOGIA Año: 2022 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Piperazinas / Proteína ADAMTS5 Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Osteoarthritis Cartilage Asunto de la revista: ORTOPEDIA / REUMATOLOGIA Año: 2022 Tipo del documento: Article