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Pharmacological blockade of the EP3 prostaglandin E2 receptor in the setting of type 2 diabetes enhances ß-cell proliferation and identity and relieves oxidative damage.
Bosma, Karin J; Andrei, Spencer R; Katz, Liora S; Smith, Ashley A; Dunn, Jennifer C; Ricciardi, Valerie F; Ramirez, Marisol A; Baumel-Alterzon, Sharon; Pace, William A; Carroll, Darian T; Overway, Emily M; Wolf, Elysa M; Kimple, Michelle E; Sheng, Quanhu; Scott, Donald K; Breyer, Richard M; Gannon, Maureen.
Afiliación
  • Bosma KJ; Dept. of Veterans Affairs Tennessee Valley Authority, Nashville, TN, USA; Dept. of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Andrei SR; Dept. of Veterans Affairs Tennessee Valley Authority, Nashville, TN, USA; Dept. of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Katz LS; Diabetes, Obesity and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Smith AA; Dept. of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA.
  • Dunn JC; Dept. of Veterans Affairs Tennessee Valley Authority, Nashville, TN, USA; Dept. of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Ricciardi VF; Dept. of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Ramirez MA; Center for Quantitative Sciences, Vanderbilt University Medical Center, Nashville, TN, USA; Dept. of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Baumel-Alterzon S; Diabetes, Obesity and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Pace WA; Dept. of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA.
  • Carroll DT; Dept. of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA.
  • Overway EM; Dept. of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA.
  • Wolf EM; Program in Cancer Biology, Vanderbilt University, Nashville, TN, USA.
  • Kimple ME; Dept. of Medicine, University of Wisconsin, Madison, WI, USA; William S. Middleton Memorial Veterans Hospital, Madison, WI, USA.
  • Sheng Q; Center for Quantitative Sciences, Vanderbilt University Medical Center, Nashville, TN, USA; Dept. of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Scott DK; Diabetes, Obesity and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Breyer RM; Dept. of Veterans Affairs Tennessee Valley Authority, Nashville, TN, USA; Dept. of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Gannon M; Dept. of Veterans Affairs Tennessee Valley Authority, Nashville, TN, USA; Dept. of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA; Dept. of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA. Electronic address: Maureen.gannon@vumc.org.
Mol Metab ; 54: 101347, 2021 12.
Article en En | MEDLINE | ID: mdl-34626853
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Diabetes Mellitus Tipo 2 / Células Secretoras de Insulina / Subtipo EP3 de Receptores de Prostaglandina E Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Mol Metab Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Diabetes Mellitus Tipo 2 / Células Secretoras de Insulina / Subtipo EP3 de Receptores de Prostaglandina E Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Mol Metab Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos