Novel bi-allelic variants in ACTL7A are associated with male infertility and total fertilization failure.

Wang, Jing; Zhang, Jintao; Sun, Xueping; Lin, Yuting; Cai, Lingbo; Cui, Yugui; Liu, Jiayin; Liu, Mingxi; Yang, Xiaoyu

Wang, Jing; Zhang, Jintao; Sun, Xueping; Lin, Yuting; Cai, Lingbo; Cui, Yugui; Liu, Jiayin; Liu, Mingxi; Yang, Xiaoyu.

Afiliación

Wang J; State Key Laboratory of Reproductive Medicine, The Center for Clinical Reproductive Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Zhang J; State Key Laboratory of Reproductive Medicine, Department of Histology and Embryology, School of Basic Medical Sciences, Nanjing Medical University, Nanjing, China.
Sun X; State Key Laboratory of Reproductive Medicine, The Center for Clinical Reproductive Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Lin Y; State Key Laboratory of Reproductive Medicine, The Center for Clinical Reproductive Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Cai L; State Key Laboratory of Reproductive Medicine, The Center for Clinical Reproductive Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Cui Y; State Key Laboratory of Reproductive Medicine, The Center for Clinical Reproductive Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Liu J; State Key Laboratory of Reproductive Medicine, The Center for Clinical Reproductive Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Liu M; State Key Laboratory of Reproductive Medicine, Department of Histology and Embryology, School of Basic Medical Sciences, Nanjing Medical University, Nanjing, China.
Yang X; State Key Laboratory of Reproductive Medicine, The Center for Clinical Reproductive Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

Hum Reprod ; 36(12): 3161-3169, 2021 11 18.

Article en En | MEDLINE | ID: mdl-34727571

Asunto(s)

Infertilidad Masculina; Acrosoma; Femenino; Fertilización/genética; Humanos; Infertilidad Masculina/genética; Infertilidad Masculina/metabolismo; Masculino; Oocitos; Embarazo; Espermatozoides/metabolismo

Palabras clave

acrosome deficiency; actin-like protein 7A; artificial oocyte activation; male infertility; total fertilization failure; variant

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Infertilidad Masculina Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Female / Humans / Male / Pregnancy Idioma: En Revista: Hum Reprod Asunto de la revista: MEDICINA REPRODUTIVA Año: 2021 Tipo del documento: Article País de afiliación: China

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