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Magnetically recoverable nickel-palladium alloy nanocatalysts for direct C-H arylation reactions.
Zozik, Yunus; Sevim, Melike; Lafzi, Ferruh; Kilic, Haydar; Metin, Önder.
Afiliación
  • Zozik Y; Department of Chemistry, Faculty of Science, Atatürk University, 25240, Erzurum, Turkey. hydk@atauni.edu.tr.
  • Sevim M; Oltu Vocational Training School, 25400, Oltu, Erzurum, Turkey.
  • Lafzi F; Department of Chemistry, Faculty of Science, Atatürk University, 25240, Erzurum, Turkey. hydk@atauni.edu.tr.
  • Kilic H; Department of Nanoscience and Nanoengineering, Atatürk University, 25240, Erzurum, Turkey.
  • Metin Ö; Department of Chemistry, Faculty of Science, Atatürk University, 25240, Erzurum, Turkey. hydk@atauni.edu.tr.
Dalton Trans ; 50(47): 17515-17523, 2021 Dec 07.
Article en En | MEDLINE | ID: mdl-34762086
ABSTRACT
Novel magnetically recoverable nanocatalyst comprising nickel-palladium (NiPd) alloy nanoparticles (NPs) supported on reduced graphene oxide (rGO) modified with cobalt ferrite (CoFe2O4) NPs was fabricated for the direct C-H arylation of imidazopyridine, imidazole, indolizine and furan with aryl halides. To prepare the presented catalyst, rGO nanosheets were first modified with as-synthesized CoFe2O4 NPs and then the obtained CoFe2O4-rGO nanocomposites served as a support material for the synthesis of bimetallic NiPd alloy NPs at various compositions. The obtained CoFe2O4-rGO/NiPd nanocatalysts were characterized by many advanced analytical techniques including TEM, STEM-EDS, XRD, XPS, and ICP-MS. Next, to optimize the reaction conditions, CoFe2O4-rGO/NiPd nanocatalysts with different alloy compositions and their monometallic counterparts (CoFe2O4-rGO/Ni and CoFe2O4-rGO/Pd) were initially tested in the direct C-H arylation of imidazopyridine with bromobenzene. Among all tested nanocatalysts under the optimum reaction conditions, CoFe2O4-rGO/Ni20Pd80 showed the best catalytic activity in terms of the isolated product yields. The C-H arylation reactions were studied over a broad substrate scope (35 examples from 36 substrates) and gave the related biaryl products in good to excellent yields. Besides a broad substrate scope, the late-stage C-H arylation of zolimidine, a gastroprotective drug, was realized under the optimized reaction conditions. Moreover, the CoFe2O4-rGO/Ni20Pd80 nanocatalysts were recovered from the reaction medium using a simple magnet and reused in the C-H arylation reactions up to five consecutive runs without a significant drop in the product yield. This study shows that magnetically recoverable Pd nanoalloys are promising heterogeneous catalysts to be used in sustainable C-H functionalization reactions.

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: Dalton Trans Asunto de la revista: QUIMICA Año: 2021 Tipo del documento: Article País de afiliación: Turquía

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: Dalton Trans Asunto de la revista: QUIMICA Año: 2021 Tipo del documento: Article País de afiliación: Turquía