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Tofacitinib in juvenile idiopathic arthritis: a double-blind, placebo-controlled, withdrawal phase 3 randomised trial.
Ruperto, Nicolino; Brunner, Hermine I; Synoverska, Olga; Ting, Tracy V; Mendoza, Carlos Abud; Spindler, Alberto; Vyzhga, Yulia; Marzan, Katherine; Grebenkina, Lyudmila; Tirosh, Irit; Imundo, Lisa; Jerath, Rita; Kingsbury, Daniel J; Sozeri, Betul; Vora, Sheetal S; Prahalad, Sampath; Zholobova, Elena; Butbul Aviel, Yonatan; Chasnyk, Vyacheslav; Lerman, Melissa; Nanda, Kabita; Schmeling, Heinrike; Tory, Heather; Uziel, Yosef; Viola, Diego O; Posner, Holly B; Kanik, Keith S; Wouters, Ann; Chang, Cheng; Zhang, Richard; Lazariciu, Irina; Hsu, Ming-Ann; Suehiro, Ricardo M; Martini, Alberto; Lovell, Daniel J.
Afiliación
  • Ruperto N; IRCCS Istituto Giannina Gaslini, UOSID Centro Trial, PRINTO, Genova, Italy. Electronic address: nicolaruperto@gaslini.org.
  • Brunner HI; College of Medicine, University of Cincinnati, and Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
  • Synoverska O; Regional Children's Hospital, Ivano-Frankivsk, Ukraine.
  • Ting TV; College of Medicine, University of Cincinnati, and Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
  • Mendoza CA; Regional Unit of Rheumatology and Osteoporosis at Central Hospital, Faculty of Medicine, San Luis Potosí, Mexico.
  • Spindler A; Centro Médico Privado de Reumatologia, Tucumán, Argentina.
  • Vyzhga Y; Vinnytsya National Medical University N Pirogov, Vinnytsya, Ukraine.
  • Marzan K; Division of Rheumatology, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
  • Grebenkina L; Togliatti City Clinical Hospital number 5, Togliatti, Russia.
  • Tirosh I; Pediatric Rheumatology Unit and Department of Pediatrics, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel-Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
  • Imundo L; Adolescent Rheumatology Columbia University Medical Center, New York, NY, USA.
  • Jerath R; Augusta University Medical Center, Augusta, GA, USA.
  • Kingsbury DJ; Augusta University Medical Center, Augusta, GA, USA; Randall Children's Hospital at Legacy Emanuel, Portland, OR, USA.
  • Sozeri B; Department of Pediatric Rheumatology, Ümraniye Training and Research Hospital, Istanbul, Turkey.
  • Vora SS; Pediatric Rheumatology, Atrium Health Levine Children's Hospital, Charlotte, NC, USA.
  • Prahalad S; Departments of Pediatrics and Human Genetics, Emory University School of Medicine, and Children's Healthcare of Atlanta, Atlanta, GA, USA.
  • Zholobova E; Institute of Children's Health, University Children's Clinical Hospital, Sechenov University, Moscow, Russia.
  • Butbul Aviel Y; Pediatric Rheumatology Service, Ruth Rappaport Children's Hospital, Rambam Medical Center, Haifa, Israel.
  • Chasnyk V; Saint Petersburg State Pediatric Medical University, Saint-Petersburg, Russia.
  • Lerman M; Division of Rheumatology, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Nanda K; Division of Rheumatology, Seattle Children's Hospital, Seattle, WA, USA.
  • Schmeling H; Department of Pediatrics, Alberta Children's Hospital, University of Calgary, Calgary, AB, Canada.
  • Tory H; Division of Rheumatology, Connecticut Children's Medical Center, Hartford, and Department of Pediatrics, University of Connecticut School of Medicine, Farmington, CT, USA.
  • Uziel Y; Pediatric Rheumatology Unit, Department of Pediatrics, Meir Medical Centre, Kfar Saba, and Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
  • Viola DO; CAICI Institute, Rosario City, Argentina.
  • Posner HB; Pfizer, New York, NY, USA.
  • Kanik KS; Pfizer, Groton, CT, USA.
  • Wouters A; Pfizer, New York, NY, USA.
  • Chang C; Pfizer, Groton, CT, USA.
  • Zhang R; Pfizer, New York, NY, USA.
  • Lazariciu I; Pfizer, New York, NY, USA.
  • Hsu MA; Pfizer, Groton, CT, USA.
  • Suehiro RM; Pfizer, Collegeville, PA, USA.
  • Martini A; Università degli Studi di Genova, Genova, Italy.
  • Lovell DJ; College of Medicine, University of Cincinnati, and Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Lancet ; 398(10315): 1984-1996, 2021 11 27.
Article en En | MEDLINE | ID: mdl-34767764
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Piperidinas / Artritis Juvenil / Pirimidinas / Inhibidores de las Cinasas Janus Tipo de estudio: Clinical_trials Límite: Adolescent / Child / Child, preschool / Humans Idioma: En Revista: Lancet Año: 2021 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Piperidinas / Artritis Juvenil / Pirimidinas / Inhibidores de las Cinasas Janus Tipo de estudio: Clinical_trials Límite: Adolescent / Child / Child, preschool / Humans Idioma: En Revista: Lancet Año: 2021 Tipo del documento: Article