Observation of substrate diffusion and ligand binding in enzyme crystals using high-repetition-rate mix-and-inject serial crystallography.
IUCrJ
; 8(Pt 6): 878-895, 2021 Nov 01.
Article
en En
| MEDLINE
| ID: mdl-34804542
European X-ray Free-Electron Laser; X-ray crystallography; antibiotic resistance; ceftriaxone; drug discovery; enzyme kinetics; enzyme mechanisms; irreversible inhibition; megahertz pulse-repetition rate; mix-and-inject serial crystallography; protein structure determination; serial femtosecond crystallography; substrate diffusion in crystals; sulbactam; ß-lactamases
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Idioma:
En
Revista:
IUCrJ
Año:
2021
Tipo del documento:
Article
País de afiliación:
Estados Unidos