Your browser doesn't support javascript.
loading
Meta-Analysis of Sleep Deprivation Effects on Patients With Depression.
Hu, Baiqi; Liu, Chunyan; Mou, Tingting; Luo, Fangyi; Lv, Tingting; Qian, Chao; Zhang, Jian; Ye, Mengfei; Liu, Zheng.
Afiliación
  • Hu B; Department of Psychiatry, Shaoxing Seventh People's Hospital, Affiliated Mental Health Center, Medical College of Shaoxing University, Shaoxing, China.
  • Liu C; Department of Behavioral Neurosciences, Science Research Center of Medical School, Shaoxing University, Shaoxing, China.
  • Mou T; Department of Neurology, Shaoxing Hospital, China Medical University, Shaoxing, China.
  • Luo F; Department of Orthopedics, Shaoxing People's Hospital, The First Affiliated Hospital of Shaoxing University, Shaoxing, China.
  • Lv T; Department of Behavioral Neurosciences, Science Research Center of Medical School, Shaoxing University, Shaoxing, China.
  • Qian C; Department of Behavioral Neurosciences, Science Research Center of Medical School, Shaoxing University, Shaoxing, China.
  • Zhang J; Department of Behavioral Neurosciences, Science Research Center of Medical School, Shaoxing University, Shaoxing, China.
  • Ye M; Department of Psychiatry, Shaoxing Seventh People's Hospital, Affiliated Mental Health Center, Medical College of Shaoxing University, Shaoxing, China.
  • Liu Z; Department of Behavioral Neurosciences, Science Research Center of Medical School, Shaoxing University, Shaoxing, China.
Front Psychiatry ; 12: 783091, 2021.
Article en En | MEDLINE | ID: mdl-34916978
Objective: Depression is a common disorder with a high recurrence rate. Since the effect of sleep deprivation on depression in existing studies were inconsistent, the present study aimed to reassess the effects of SD on patients by performing a meta-analysis of updated research. Methods: PubMed, Embase, the Cochrane Library, and Web of Science were searched for articles before January 20th, 2021. Data on participant characteristics, SD characteristics, adjunctive method and tests for depression were extracted. A comprehensive analysis was conducted to assess the effect of SD on depression and subgroup analysis was used to determine the sources of heterogeneity. Results: In total, 8 articles were included. An SD time of <7 days slightly worsened depression levels [0.24 (-0.21, 0.69); I 2 = 0%; P = 0.43], a time of 7-14 days had antidepressant effects [-1.52 (-2.07, -0.97); I 2 = 19.6%; P = 0.288], and a time of more than 14 days also worsened depression [0.76 (0.12, 1.40); I 2 = 43.7%; P = 0.169]. Conclusion: SD may serve as an effective antidepressant measure in humans when the time was 7-14 days, while a time of <7 days and more than 14 days worsened depression.
Palabras clave

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Tipo de estudio: Systematic_reviews Idioma: En Revista: Front Psychiatry Año: 2021 Tipo del documento: Article País de afiliación: China

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Tipo de estudio: Systematic_reviews Idioma: En Revista: Front Psychiatry Año: 2021 Tipo del documento: Article País de afiliación: China