Epigenomic and Transcriptomic Prioritization of Candidate Obesity-Risk Regulatory GWAS SNPs.

Zhang, Xiao; Li, Tian-Ying; Xiao, Hong-Mei; Ehrlich, Kenneth C; Shen, Hui; Deng, Hong-Wen; Ehrlich, Melanie

Zhang, Xiao; Li, Tian-Ying; Xiao, Hong-Mei; Ehrlich, Kenneth C; Shen, Hui; Deng, Hong-Wen; Ehrlich, Melanie.

Afiliación

Zhang X; Tulane Center for Biomedical Informatics and Genomics, Division of Biomedical Informatics and Genomics, Deming Department of Medicine, School of Medicine, Tulane University, New Orleans, LA 70112, USA.
Li TY; Center for System Biology, Data Sciences, and Reproductive Health, School of Basic Medical Science, Central South University, Changsha 410013, China.
Xiao HM; Center for System Biology, Data Sciences, and Reproductive Health, School of Basic Medical Science, Central South University, Changsha 410013, China.
Ehrlich KC; Tulane Center for Biomedical Informatics and Genomics, Division of Biomedical Informatics and Genomics, Deming Department of Medicine, School of Medicine, Tulane University, New Orleans, LA 70112, USA.
Shen H; Tulane Center for Biomedical Informatics and Genomics, Division of Biomedical Informatics and Genomics, Deming Department of Medicine, School of Medicine, Tulane University, New Orleans, LA 70112, USA.
Deng HW; Tulane Center for Biomedical Informatics and Genomics, Division of Biomedical Informatics and Genomics, Deming Department of Medicine, School of Medicine, Tulane University, New Orleans, LA 70112, USA.
Ehrlich M; Tulane Center for Biomedical Informatics and Genomics, Division of Biomedical Informatics and Genomics, Deming Department of Medicine, School of Medicine, Tulane University, New Orleans, LA 70112, USA.

Int J Mol Sci ; 23(3)2022 Jan 23.

Article en En | MEDLINE | ID: mdl-35163195

Asunto(s)

Biología Computacional/métodos; Estudio de Asociación del Genoma Completo/métodos; Obesidad/genética; Polimorfismo de Nucleótido Simple/genética; Cromatina/genética; Epigénesis Genética/genética; Epigenómica/métodos; Expresión Génica/genética; Perfilación de la Expresión Génica/métodos; Regulación de la Expresión Génica/genética; Predisposición Genética a la Enfermedad/genética; Humanos; Desequilibrio de Ligamiento/genética; Obesidad/metabolismo; Sitios de Carácter Cuantitativo/genética; Factores de Transcripción/metabolismo; Transcriptoma/genética

Palabras clave

GWAS; RNA isoforms; SNPs; enhancers; epigenetics; lncRNA; obesity; promoters; subcutaneous adipose tissue; transcriptomics

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Biología Computacional / Polimorfismo de Nucleótido Simple / Estudio de Asociación del Genoma Completo / Obesidad Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Int J Mol Sci Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos

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