Ubiquitin-specific protease 8 inhibits lipopolysaccharide-triggered pyroptosis of human bronchial epithelial cells by regulating PI3K/AKT and NF-&#954;B pathways.

Liu, Lu; Huan, Liting; Zhang, Yu; Wei, Wei; Chen, Zhihai; Xu, Di; Huang, Xiufeng; Tan, Yaoxi; Li, Hongxing

Ubiquitin-specific protease 8 inhibits lipopolysaccharide-triggered pyroptosis of human bronchial epithelial cells by regulating PI3K/AKT and NF-κB pathways.

Liu, Lu; Huan, Liting; Zhang, Yu; Wei, Wei; Chen, Zhihai; Xu, Di; Huang, Xiufeng; Tan, Yaoxi; Li, Hongxing.

Afiliación

Liu L; Department of Respiratory and Critical Care Medicine, Wuxi 9th People's Hospital Affiliated to Soochow University, Wuxi, China; Liulu_1221@163.com.
Huan L; Department of Internal Medicine, Zibo Municipal Hospital for Infectious Diseases, Zibo, China.
Zhang Y; Department of Respiratory and Critical Care Medicine, Wuxi 9th People's Hospital Affiliated to Soochow University, Wuxi, China.
Wei W; Department of Respiratory and Critical Care Medicine, Wuxi 9th People's Hospital Affiliated to Soochow University, Wuxi, China.
Chen Z; Department of Respiratory and Critical Care Medicine, Wuxi 9th People's Hospital Affiliated to Soochow University, Wuxi, China.
Xu D; Department of Respiratory and Critical Care Medicine, Wuxi 9th People's Hospital Affiliated to Soochow University, Wuxi, China.
Huang X; Department of Respiratory and Critical Care Medicine, Wuxi 9th People's Hospital Affiliated to Soochow University, Wuxi, China.
Tan Y; Department of Respiratory and Critical Care Medicine, Wuxi 9th People's Hospital Affiliated to Soochow University, Wuxi, China.
Li H; Department of Respiratory and Critical Care Medicine, Wuxi 9th People's Hospital Affiliated to Soochow University, Wuxi, China.

Allergol Immunopathol (Madr) ; 50(2): 96-103, 2022.

Article en En | MEDLINE | ID: mdl-35257552

Asunto(s)

Lipopolisacáridos; FN-kappa B; Células Epiteliales/metabolismo; Humanos; Lipopolisacáridos/metabolismo; Lipopolisacáridos/farmacología; FN-kappa B/metabolismo; Fosfatidilinositol 3-Quinasas/metabolismo; Proteínas Proto-Oncogénicas c-akt/metabolismo; Piroptosis; Proteasas Ubiquitina-Específicas/metabolismo; Proteasas Ubiquitina-Específicas/farmacología

Palabras clave

NF-κB; PI3K/AKT; asthma; human bronchial epithelial cells; inflammation; lipopolysaccharide; pyroptosis; ubiquitin-specific protease 8

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Lipopolisacáridos / FN-kappa B Límite: Humans Idioma: En Revista: Allergol Immunopathol (Madr) Año: 2022 Tipo del documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google