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American Head and Neck Society Endocrine Surgery Section and International Thyroid Oncology Group consensus statement on mutational testing in thyroid cancer: Defining advanced thyroid cancer and its targeted treatment.
Shonka, David C; Ho, Alan; Chintakuntlawar, Ashish V; Geiger, Jessica L; Park, Jong C; Seetharamu, Nagashree; Jasim, Sina; Abdelhamid Ahmed, Amr H; Bible, Keith C; Brose, Marcia S; Cabanillas, Maria E; Dabekaussen, Kirsten; Davies, Louise; Dias-Santagata, Dora; Fagin, James A; Faquin, William C; Ghossein, Ronald A; Gopal, Raj K; Miyauchi, Akira; Nikiforov, Yuri E; Ringel, Matthew D; Robinson, Bruce; Ryder, Mabel M; Sherman, Eric J; Sadow, Peter M; Shin, Jennifer J; Stack, Brendan C; Tuttle, R Michael; Wirth, Lori J; Zafereo, Mark E; Randolph, Gregory W.
Afiliación
  • Shonka DC; Department of Otolaryngology - Head and Neck Surgery, University of Virginia, Charlottesville, Virginia, USA.
  • Ho A; Department of Hematology and Medical Oncology, Solid Tumor Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
  • Chintakuntlawar AV; Division of Medical Oncology, Mayo Clinic, Rochester, Minnesota, USA.
  • Geiger JL; Department of Hematology and Medical Oncology, Cleveland Clinic Taussig Cancer Institute, Cleveland, Ohio, USA.
  • Park JC; Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.
  • Seetharamu N; Division of Hematology-Oncology, Donald and Barbara Zucker School of Medicine at Hofstra University, New Hyde Park, New York, USA.
  • Jasim S; Division of Endocrinology, Metabolism and Lipid Research, Department of Internal Medicine, School of Medicine, Washington University in St. Louis, Saint Louis, Missouri, USA.
  • Abdelhamid Ahmed AH; Department of Otolaryngology - Head and Neck Surgery, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, USA.
  • Bible KC; Division of Medical Oncology, Mayo Clinic, Rochester, Minnesota, USA.
  • Brose MS; Abramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Cabanillas ME; Department of Endocrine Neoplasia and Hormonal Disorders, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA.
  • Dabekaussen K; Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
  • Davies L; Department of Surgery, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.
  • Dias-Santagata D; Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
  • Fagin JA; Endocrinology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
  • Faquin WC; Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
  • Ghossein RA; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
  • Gopal RK; Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.
  • Miyauchi A; Department of Surgery, Kuma Hospital, Kobe, Japan.
  • Nikiforov YE; Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
  • Ringel MD; Division of Endocrinology, Diabetes, and Metabolism, The Ohio State University Medical Center, Columbus, Ohio, USA.
  • Robinson B; Northern Clinical School, Sydney Medical School, Faculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia.
  • Ryder MM; Division of Endocrinology, Diabetes, Metabolism, & Nutrition, Mayo Clinic, Rochester, Minnesota, USA.
  • Sherman EJ; Head and Neck Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
  • Sadow PM; Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
  • Shin JJ; Department of Otolaryngology - Head and Neck Surgery, Center for Surgery and Public Health, Harvard Medical School, Boston, Massachusetts, USA.
  • Stack BC; Department of Otolaryngology - Head and Neck Surgery, Southern Illinois University School of Medicine, Springfield, Illinois, USA.
  • Tuttle RM; Endocrinology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
  • Wirth LJ; Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.
  • Zafereo ME; Department of Head and Neck Surgery, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA.
  • Randolph GW; Department of Otolaryngology - Head and Neck Surgery, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, USA.
Head Neck ; 44(6): 1277-1300, 2022 06.
Article en En | MEDLINE | ID: mdl-35274388
ABSTRACT

BACKGROUND:

The development of systemic treatment options leveraging the molecular landscape of advanced thyroid cancer is a burgeoning field. This is a multidisciplinary evidence-based statement on the definition of advanced thyroid cancer and its targeted systemic treatment.

METHODS:

An expert panel was assembled, a literature review was conducted, and best practice statements were developed. The modified Delphi method was applied to assess the degree of consensus for the statements developed by the author panel.

RESULTS:

A review of the current understanding of thyroid oncogenesis at a molecular level is presented and characteristics of advanced thyroid cancer are defined. Twenty statements in topics including the multidisciplinary management, molecular evaluation, and targeted systemic treatment of advanced thyroid cancer are provided.

CONCLUSIONS:

With the growth in targeted treatment options for thyroid cancer, a consensus definition of advanced disease and statements regarding the utility of molecular testing and available targeted systemic therapy is warranted.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias de la Tiroides Tipo de estudio: Guideline Límite: Humans País/Región como asunto: America do norte Idioma: En Revista: Head Neck Asunto de la revista: NEOPLASIAS Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias de la Tiroides Tipo de estudio: Guideline Límite: Humans País/Región como asunto: America do norte Idioma: En Revista: Head Neck Asunto de la revista: NEOPLASIAS Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos