Rampant C-to-U deamination accounts for the intrinsically high mutation rate in SARS-CoV-2 spike gene.

Liu, Xueyan; Liu, Xuan; Zhou, Jie; Dong, Yu; Jiang, Wen; Jiang, Wenqing

Liu, Xueyan; Liu, Xuan; Zhou, Jie; Dong, Yu; Jiang, Wen; Jiang, Wenqing.

Afiliación

Liu X; Institute of Integrative Medicine, School of Basic Medicine, Qingdao University, Qingdao, Shandong 266073, China.
Liu X; Department of Disease Prevention, Qingdao Hiser Medical Group, Qingdao, Shandong 266033, China.
Zhou J; Respiratory and Critical Illness Medicine Department II, Qingdao Hiser Medical Group, Qingdao, Shandong 266033, China.
Dong Y; Nursing Department, Qingdao Central Hospital, Qingdao, Shandong 266042, China.
Jiang W; Interventional Catheterization Lab, Qingdao Central Hospital, Qingdao, Shandong 266042, China.
Jiang W; Respiratory and Critical Illness Medicine Department II, Qingdao Hiser Medical Group, Qingdao, Shandong 266033, China.

RNA ; 28(7): 917-926, 2022 07.

Article en En | MEDLINE | ID: mdl-35508354

Asunto(s)

COVID-19; SARS-CoV-2; COVID-19/genética; Desaminación; Humanos; Mutación; Tasa de Mutación; Pandemias; SARS-CoV-2/genética

Palabras clave

C-to-U deamination; S gene; SARS-CoV-2; mutation rate; single-stranded RNA

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: SARS-CoV-2 / COVID-19 Límite: Humans Idioma: En Revista: RNA Asunto de la revista: BIOLOGIA MOLECULAR Año: 2022 Tipo del documento: Article País de afiliación: China

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