Juvenile psammomatoid ossifying fibroma of the parietal bone and review of calvarial presentations: illustrative case.
J Neurosurg Case Lessons
; 2(10): CASE21361, 2021 Sep 06.
Article
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| MEDLINE
| ID: mdl-35855183
ABSTRACT
BACKGROUND:
Juvenile psammomatoid ossifying fibroma (JPOF) is an uncommon benign fibro-osseous lesion that only rarely presents in the calvaria. OBSERVATIONS The authors reported a case of JPOF in the left parietal bone of a 20-year-old patient and reviewed the 27 other cases of JPOF occurring in the calvaria as reported in the literature. LESSONS JPOF rarely presents in the calvaria, and because diagnosis is a histopathologic one, clinicians should consider this entity when presented with a lytic, expansile mass on imaging. Little is known about the molecular mechanisms driving development of JPOF. MDM2 amplification may play a role, although this was not seen in the case presented herein.
COF = cemento-ossifying fibroma; CT = computed tomography; EMA = epithelial membrane antigen; FISH = fluorescence in situ hybridization; JPOF; JPOF = juvenile psammomatoid ossifying fibroma; MRI = magnetic resonance imaging; PR = progesterone receptor; juvenile active ossifying fibroma; juvenile psammomatoid ossifying fibroma; ossifying fibroma
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1
Colección:
01-internacional
Banco de datos:
MEDLINE
Idioma:
En
Revista:
J Neurosurg Case Lessons
Año:
2021
Tipo del documento:
Article