Primary failure of tooth eruption: Etiology and management.
Jpn Dent Sci Rev
; 58: 258-267, 2022 Nov.
Article
en En
| MEDLINE
| ID: mdl-36159186
ABSTRACT
Primary failure of eruption (PFE) is a rare disorder defined as incomplete tooth eruption despite the presence of a clear eruption pathway. PFE is known to be caused by rare variants in the parathyroid hormone 1 receptor gene (PTH1R). Although several PTH1R variants have been reported, the etiology of PFE remains unclear. However, important studies that help elucidate the pathology of PFE have recently been published. The purpose of this review is to summarize current treatment options, clinical symptoms or phenotypes for diagnosis, genetic information including solid evidence in mouse disease models and disease-specific induced pluripotent stem cells, thus approaching the etiology of PFE from the perspective of the latest research.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Tipo de estudio:
Etiology_studies
Idioma:
En
Revista:
Jpn Dent Sci Rev
Año:
2022
Tipo del documento:
Article
País de afiliación:
Japón