A NiCoT family metal transporter of <i>Mycobacterium tuberculosis</i> (Rv2856/NicT) behaves as a drug efflux pump that facilitates cross-resistance to antibiotics.

Adhikary, Anwesha; Biswal, Sarmistha; Chatterjee, Debasmita; Ghosh, Anindya S

A NiCoT family metal transporter of Mycobacterium tuberculosis (Rv2856/NicT) behaves as a drug efflux pump that facilitates cross-resistance to antibiotics.

Adhikary, Anwesha; Biswal, Sarmistha; Chatterjee, Debasmita; Ghosh, Anindya S.

Afiliación

Adhikary A; Department of Biotechnology, Indian Institute of Technology Kharagpur, Kharagpur, West Bengal-721302, India.
Biswal S; Department of Biotechnology, Indian Institute of Technology Kharagpur, Kharagpur, West Bengal-721302, India.
Chatterjee D; Department of Biotechnology, Indian Institute of Technology Kharagpur, Kharagpur, West Bengal-721302, India.
Ghosh AS; Department of Biotechnology, Indian Institute of Technology Kharagpur, Kharagpur, West Bengal-721302, India.

Microbiology (Reading) ; 168(10)2022 10.

Article en En | MEDLINE | ID: mdl-36282241

Asunto(s)

Mycobacterium tuberculosis; Mycobacterium tuberculosis/genética; Mycobacterium tuberculosis/metabolismo; Antibacterianos/farmacología; Antibacterianos/metabolismo; Isoniazida/farmacología; Etambutol; Escherichia coli/genética; Escherichia coli/metabolismo; Níquel/farmacología; Níquel/metabolismo; Norfloxacino/metabolismo; Ácido Nalidíxico; Doxiciclina; Isoleucina; Leucina; Proteínas Bacterianas/metabolismo; Proteínas de Transporte de Membrana/metabolismo; Cobalto/metabolismo; Kanamicina; Ofloxacino; Gentamicinas; Neomicina/metabolismo; Pruebas de Sensibilidad Microbiana; Farmacorresistencia Bacteriana Múltiple/genética

Palabras clave

Multidrug efflux pump; Mycobacterium tuberculosis; NiCoT family transporter; antibiotic-metal cross resistance; metal efflux pump

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Mycobacterium tuberculosis Idioma: En Revista: Microbiology (Reading) Asunto de la revista: MICROBIOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: India

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