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Anti-α-synuclein c-terminal antibodies block PFF uptake and accumulation of phospho-synuclein in preclinical models of Parkinson's disease.
Brendza, Robert; Gao, Xiaoying; Stark, Kimberly L; Lin, Han; Lee, Seung-Hye; Hu, Changyun; Cai, Hao; DiCara, Danielle; Hsiao, Yi-Chun; Ngu, Hai; Foreman, Oded; Baca, Miriam; Dohse, Monika; Fortin, Jean-Phillipe; Corpuz, Racquel; Seshasayee, Dhaya; Easton, Amy; Ayalon, Gai; Hötzel, Isidro; Chih, Ben.
Afiliación
  • Brendza R; Neuroscience, Genentech, South San Francisco, CA, USA.
  • Gao X; Biochemical and Cellular Pharmacology, Genentech, South San Francisco, CA, USA.
  • Stark KL; Neuroscience, Genentech, South San Francisco, CA, USA.
  • Lin H; Neuroscience, Genentech, South San Francisco, CA, USA.
  • Lee SH; Neuroscience, Genentech, South San Francisco, CA, USA.
  • Hu C; Antibody Engineering, Genentech, South San Francisco, CA, USA.
  • Cai H; Preclinical and Translational Pharmacokinetics, Genentech, South San Francisco, CA, USA.
  • DiCara D; Antibody Engineering, Genentech, South San Francisco, CA, USA.
  • Hsiao YC; Antibody Engineering, Genentech, South San Francisco, CA, USA.
  • Ngu H; Pathology, Genentech, South San Francisco, CA, USA.
  • Foreman O; Pathology, Genentech, South San Francisco, CA, USA.
  • Baca M; Pathology, Genentech, South San Francisco, CA, USA.
  • Dohse M; Pathology, Genentech, South San Francisco, CA, USA.
  • Fortin JP; Statistics, Genentech, South San Francisco, USA.
  • Corpuz R; Antibody Engineering, Genentech, South San Francisco, CA, USA.
  • Seshasayee D; Antibody Engineering, Genentech, South San Francisco, CA, USA.
  • Easton A; Neuroscience, Genentech, South San Francisco, CA, USA. Electronic address: amy.easton@targetals.org.
  • Ayalon G; Neuroscience, Genentech, South San Francisco, CA, USA.
  • Hötzel I; Antibody Engineering, Genentech, South San Francisco, CA, USA.
  • Chih B; Biochemical and Cellular Pharmacology, Genentech, South San Francisco, CA, USA. Electronic address: ben.chih@gmail.com.
Neurobiol Dis ; 177: 105969, 2023 02.
Article en En | MEDLINE | ID: mdl-36535551
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Enfermedad de Parkinson / Enfermedades Neurodegenerativas / Sinucleinopatías Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Neurobiol Dis Asunto de la revista: NEUROLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Enfermedad de Parkinson / Enfermedades Neurodegenerativas / Sinucleinopatías Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Neurobiol Dis Asunto de la revista: NEUROLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos