Analysis of a degron-containing reporter protein GFP-CL1 reveals a role for SUMO1 in cytosolic protein quality control.

Wang, Wei; Lu, Jian; Yang, Wei-Chih; Spear, Eric D; Michaelis, Susan; Matunis, Michael J

Wang, Wei; Lu, Jian; Yang, Wei-Chih; Spear, Eric D; Michaelis, Susan; Matunis, Michael J.

Afiliación

Wang W; Department of Biochemistry and Molecular Biology, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, Maryland, USA.
Lu J; Department of Biochemistry and Molecular Biology, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, Maryland, USA.
Yang WC; Department of Biochemistry and Molecular Biology, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, Maryland, USA.
Spear ED; Department of Cell Biology, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA.
Michaelis S; Department of Cell Biology, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA.
Matunis MJ; Department of Biochemistry and Molecular Biology, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, Maryland, USA. Electronic address: mmatuni1@jhu.edu.

J Biol Chem ; 299(2): 102851, 2023 02.

Article en En | MEDLINE | ID: mdl-36587767

Asunto(s)

Proteolisis; Proteína SUMO-1; Proteínas de Saccharomyces cerevisiae; Saccharomyces cerevisiae; Animales; Humanos; Citoplasma/metabolismo; Citosol/metabolismo; Proteínas Nucleares/metabolismo; Saccharomyces cerevisiae/genética; Saccharomyces cerevisiae/metabolismo; Proteínas de Saccharomyces cerevisiae/genética; Proteínas de Saccharomyces cerevisiae/metabolismo; Proteína SUMO-1/genética; Proteína SUMO-1/metabolismo

Palabras clave

CL1 degron; Cdc48/p97; protein quality control; small ubiquitin-like modifier; ubiquitin-proteasome system (UPS)

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Saccharomyces cerevisiae / Proteínas de Saccharomyces cerevisiae / Proteína SUMO-1 / Proteolisis Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: J Biol Chem Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos

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