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Discovery of IHMT-337 as a potent irreversible EZH2 inhibitor targeting CDK4 transcription for malignancies.
Mei, Husheng; Wu, Hong; Yang, Jing; Zhou, Bin; Wang, Aoli; Hu, Chen; Qi, Shuang; Jiang, Zongru; Zou, Fengming; Wang, Beilei; Liu, Feiyang; Chen, Yongfei; Wang, Wenchao; Liu, Jing; Liu, Qingsong.
Afiliación
  • Mei H; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, 230031, Hefei, Anhui, P. R. China.
  • Wu H; University of Science and Technology of China, 230026, Hefei, Anhui, P. R. China.
  • Yang J; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, 230031, Hefei, Anhui, P. R. China.
  • Zhou B; Hefei Cancer Hospital, Chinese Academy of Sciences, 230031, Hefei, Anhui, P. R. China.
  • Wang A; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, 230031, Hefei, Anhui, P. R. China.
  • Hu C; Hefei Cancer Hospital, Chinese Academy of Sciences, 230031, Hefei, Anhui, P. R. China.
  • Qi S; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, 230031, Hefei, Anhui, P. R. China.
  • Jiang Z; University of Science and Technology of China, 230026, Hefei, Anhui, P. R. China.
  • Zou F; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, 230031, Hefei, Anhui, P. R. China.
  • Wang B; Hefei Cancer Hospital, Chinese Academy of Sciences, 230031, Hefei, Anhui, P. R. China.
  • Liu F; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, 230031, Hefei, Anhui, P. R. China.
  • Chen Y; Hefei Cancer Hospital, Chinese Academy of Sciences, 230031, Hefei, Anhui, P. R. China.
  • Wang W; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, 230031, Hefei, Anhui, P. R. China.
  • Liu J; Hefei Cancer Hospital, Chinese Academy of Sciences, 230031, Hefei, Anhui, P. R. China.
  • Liu Q; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, 230031, Hefei, Anhui, P. R. China.
Signal Transduct Target Ther ; 8(1): 18, 2023 01 16.
Article en En | MEDLINE | ID: mdl-36642705

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Linfoma de Células B Grandes Difuso / Neoplasias de la Mama Triple Negativas Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Signal Transduct Target Ther Año: 2023 Tipo del documento: Article

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Linfoma de Células B Grandes Difuso / Neoplasias de la Mama Triple Negativas Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Signal Transduct Target Ther Año: 2023 Tipo del documento: Article