Recent Advancements in Electroporation Technologies: From Bench to Clinic.
Annu Rev Biomed Eng
; 25: 77-100, 2023 06 08.
Article
en En
| MEDLINE
| ID: mdl-36854260
ABSTRACT
Over the past decade, the increased adoption of electroporation-based technologies has led to an expansion of clinical research initiatives. Electroporation has been utilized in molecular biology for mammalian and bacterial transfection; for food sanitation; and in therapeutic settings to increase drug uptake, for gene therapy, and to eliminate cancerous tissues. We begin this article by discussing the biophysics required for understanding the concepts behind the cell permeation phenomenon that is electroporation. We then review nano- and microscale single-cell electroporation technologies before scaling up to emerging in vivo applications.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Electroquimioterapia
/
Neoplasias
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Annu Rev Biomed Eng
Asunto de la revista:
ENGENHARIA BIOMEDICA
Año:
2023
Tipo del documento:
Article