Pancreatic stellate cells promote pancreatic ß-cell death through exosomal microRNA transfer in hypoxia.

Lee, Esder; Ryu, Gyeong Ryul; Ko, Seung-Hyun; Ahn, Yu-Bae; Song, Ki-Ho

Lee, Esder; Ryu, Gyeong Ryul; Ko, Seung-Hyun; Ahn, Yu-Bae; Song, Ki-Ho.

Afiliación

Lee E; Division of Endocrinology & Metabolism, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
Ryu GR; Division of Endocrinology & Metabolism, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
Ko SH; Division of Endocrinology & Metabolism, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
Ahn YB; Division of Endocrinology & Metabolism, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
Song KH; Division of Endocrinology & Metabolism, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, South Korea. Electronic address: kihos@catholic.ac.kr.

Mol Cell Endocrinol ; 572: 111947, 2023 07 15.

Article en En | MEDLINE | ID: mdl-37150285

Asunto(s)

Diabetes Mellitus Tipo 2; Islotes Pancreáticos; MicroARNs; Ratones; Animales; MicroARNs/genética; MicroARNs/metabolismo; Diabetes Mellitus Tipo 2/metabolismo; Células Estrelladas Pancreáticas/metabolismo; Islotes Pancreáticos/metabolismo; Insulina/metabolismo; Glucosa/metabolismo; Hipoxia/metabolismo; Muerte Celular

Palabras clave

Exosome; Hypoxia; Islet; Pancreatic stellate cell; microRNA; ß-cell

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Islotes Pancreáticos / MicroARNs / Diabetes Mellitus Tipo 2 Límite: Animals Idioma: En Revista: Mol Cell Endocrinol Año: 2023 Tipo del documento: Article País de afiliación: Corea del Sur

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