The exoribonuclease XRN2 mediates degradation of the long non-coding telomeric RNA TERRA.

Reiss, Matthew; Keegan, Joshua; Aldrich, Anne; Lyons, Shawn M; Flynn, Rachel Litman

Reiss, Matthew; Keegan, Joshua; Aldrich, Anne; Lyons, Shawn M; Flynn, Rachel Litman.

Afiliación

Reiss M; Departments of Pharmacology, Physiology & Biophysics and Medicine, Cancer Center, Boston University Chobanian & Avedisian School of Medicine, MA, Boston, USA.
Keegan J; Departments of Pharmacology, Physiology & Biophysics and Medicine, Cancer Center, Boston University Chobanian & Avedisian School of Medicine, MA, Boston, USA.
Aldrich A; Departments of Biochemistry and Cell Biology, Boston University Chobanian & Avedisian School of Medicine, MA, USA.
Lyons SM; Departments of Biochemistry and Cell Biology, Boston University Chobanian & Avedisian School of Medicine, MA, USA.
Flynn RL; Departments of Pharmacology, Physiology & Biophysics and Medicine, Cancer Center, Boston University Chobanian & Avedisian School of Medicine, MA, Boston, USA.

FEBS Lett ; 597(14): 1818-1836, 2023 07.

Article en En | MEDLINE | ID: mdl-37191774

Asunto(s)

ARN Largo no Codificante; ARN Largo no Codificante/genética; ARN Largo no Codificante/metabolismo; Exorribonucleasas/genética; Telómero/genética; Telómero/metabolismo; Homeostasis del Telómero; ADN; ARN/genética

Palabras clave

R-loops; TERRA; XRN2; alternative lengthening of telomeres; auxin-inducible degron

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: ARN Largo no Codificante Tipo de estudio: Prognostic_studies Idioma: En Revista: FEBS Lett Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos

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