Analysis of dietary patterns on cardiovascular risks in children: from a cross-sectional and a longitudinal study.

ABSTRACT

OBJECTIVES: Diet is one of the main risk factors for cardiovascular disease (CVD), while the evidence about the relationship between dietary pattern (DP) and CVD in children is scarce. This study aims to explore the association between DP and CVD risk in children. STUDY DESIGN: This was a cross-sectional and longitudinal study. METHODS: This research was conducted among 4351 children aged 6-12 years old in 2014, then the subgroup children in 2014 were followed up in 2019. Dietary intakes were assessed using a food frequency questionnaire. DP was clustered based on 15 food items, and finally, four main DPs were obtained. RESULTS: Four major DPs were identified (1) low intake of nuts and algae pattern, (2) low-energy intake pattern, (3) high-energy intake pattern, and (4) regular DP. Compared with the regular diet pattern, the low intake of nuts and algae pattern was associated with the increased risk of higher systolic blood pressure (107.71 mm Hg vs 105.78 mm Hg, P < 0.001), diastolic blood pressure (64.98 mm Hg vs 63.91 mm Hg, P = 0.0056), hypertension (odds ratio [OR]1.44, 95% confidence interval [CI] 1.10, 1.88; P = 0.0036), dyslipidemia (OR 2.41, 95% CI 1.28, 4.52; P = 0.0194), and obesity (OR 1.48, 95% CI 1.16, 1.89; P = 0.0003) in children from a cross-sectional aspect in 2014 and it was also found associated with an increased risk of hypertension (OR 2.67, 95% CI 1.45, 4.92; P = 0.0017) in 2019. CONCLUSIONS: Low nuts and algae intake combinations in children seemed associated with increased CVD risk. Such findings are imperative for national development of dietary recommendation for the prevention of CVDs.