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Pregnane X receptor activation alleviates renal fibrosis in mice via interacting with p53 and inhibiting the Wnt7a/ß-catenin signaling.
Ming, Wen-Hua; Luan, Zhi-Lin; Yao, Yao; Liu, Hang-Chi; Hu, Shu-Yuan; Du, Chun-Xiu; Zhang, Cong; Zhao, Yi-Hang; Huang, Ying-Zhi; Sun, Xiao-Wan; Qiao, Rong-Fang; Xu, Hu; Guan, You-Fei; Zhang, Xiao-Yan.
Afiliación
  • Ming WH; Advanced Institute for Medical Sciences, Dalian Medical University, Dalian, 116044, China.
  • Luan ZL; Health Science Center, East China Normal University, Shanghai, 200241, China.
  • Yao Y; Advanced Institute for Medical Sciences, Dalian Medical University, Dalian, 116044, China.
  • Liu HC; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Dalian Medical University, Dalian, 116044, China.
  • Hu SY; Dalian Key Laboratory for Nuclear Receptors in Major Metabolic Diseases, Dalian, 116044, China.
  • Du CX; Department of nephrology, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong, 226006, China.
  • Zhang C; Health Science Center, East China Normal University, Shanghai, 200241, China.
  • Zhao YH; Department of nephrology, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong, 226006, China.
  • Huang YZ; Division of Nephrology, Wuhu Hospital, East China Normal University, Wuhu, 241100, China.
  • Sun XW; Advanced Institute for Medical Sciences, Dalian Medical University, Dalian, 116044, China.
  • Qiao RF; Advanced Institute for Medical Sciences, Dalian Medical University, Dalian, 116044, China.
  • Xu H; Advanced Institute for Medical Sciences, Dalian Medical University, Dalian, 116044, China.
  • Guan YF; Health Science Center, East China Normal University, Shanghai, 200241, China.
  • Zhang XY; Advanced Institute for Medical Sciences, Dalian Medical University, Dalian, 116044, China.
Acta Pharmacol Sin ; 44(10): 2075-2090, 2023 Oct.
Article en En | MEDLINE | ID: mdl-37344564
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Insuficiencia Renal Crónica / Vía de Señalización Wnt / Receptor X de Pregnano Límite: Animals / Humans Idioma: En Revista: Acta Pharmacol Sin Asunto de la revista: FARMACOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Insuficiencia Renal Crónica / Vía de Señalización Wnt / Receptor X de Pregnano Límite: Animals / Humans Idioma: En Revista: Acta Pharmacol Sin Asunto de la revista: FARMACOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: China