Glutathione-linked enzyme activities in red cell aging.

ABSTRACT

The enzyme activities of glucose-6-phosphate dehydrogenase (G6PD), 6-phospho-gluconate dehydrogenase (6PGD), glutathione peroxidase (GSH-Px) and glutathione reductase (GR) were measured in normal human red cells separated centrifugally in a discontinuous density gradient of Percoll. Activities of G6PD, GSH-Px and GR decreased with red cell aging.