Tree shrew cytochrome P450 2E1 is a functional enzyme that metabolises chlorzoxazone and <i>p</i>-nitrophenol.

Ushirozako, Genki; Murayama, Norie; Tsukiyama-Kohara, Kyoko; Yamazaki, Hiroshi; Uno, Yasuhiro

Tree shrew cytochrome P450 2E1 is a functional enzyme that metabolises chlorzoxazone and p-nitrophenol.

Ushirozako, Genki; Murayama, Norie; Tsukiyama-Kohara, Kyoko; Yamazaki, Hiroshi; Uno, Yasuhiro.

Afiliación

Ushirozako G; Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima-city, Japan.
Murayama N; Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, Tokyo, Japan.
Tsukiyama-Kohara K; Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima-city, Japan.
Yamazaki H; Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, Tokyo, Japan.
Uno Y; Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima-city, Japan.

Xenobiotica ; 53(10-11): 573-580, 2023.

Article en En | MEDLINE | ID: mdl-37934191

Asunto(s)

Citocromo P-450 CYP2E1; Tupaia; Humanos; Porcinos; Animales; Perros; Citocromo P-450 CYP2E1/genética; Citocromo P-450 CYP2E1/metabolismo; Tupaia/metabolismo; Clorzoxazona/metabolismo; Tupaiidae/metabolismo; Filogenia; Musarañas/metabolismo; Sistema Enzimático del Citocromo P-450/genética; Sistema Enzimático del Citocromo P-450/metabolismo; Microsomas Hepáticos/metabolismo

Palabras clave

CYP2E1; chlorzoxazone; dog; human; liver; p-nitrophenol; pig

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Tupaia / Citocromo P-450 CYP2E1 Límite: Animals / Humans Idioma: En Revista: Xenobiotica Año: 2023 Tipo del documento: Article País de afiliación: Japón

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