SIRT1 mediates the inhibitory effect of Dapagliflozin on EndMT by inhibiting the acetylation of endothelium Notch1.

Wang, Weijie; Li, Yilan; Zhang, Yanxiu; Ye, Tao; Wang, Kui; Li, Shuijie; Zhang, Yao

Wang, Weijie; Li, Yilan; Zhang, Yanxiu; Ye, Tao; Wang, Kui; Li, Shuijie; Zhang, Yao.

Afiliación

Wang W; Department of Cardiology, The Second Affiliated Hospital of Harbin Medical University, 246 Xuefu Road, Harbin, 150086, China.
Li Y; Key Laboratory of Myocardial Ischemia, Ministry of Education, Harbin Medical University, Harbin, China.
Zhang Y; Department of Cardiology, The Second Affiliated Hospital of Harbin Medical University, 246 Xuefu Road, Harbin, 150086, China.
Ye T; Key Laboratory of Myocardial Ischemia, Ministry of Education, Harbin Medical University, Harbin, China.
Wang K; Department of Cardiology, The Second Affiliated Hospital of Harbin Medical University, 246 Xuefu Road, Harbin, 150086, China.
Li S; Key Laboratory of Myocardial Ischemia, Ministry of Education, Harbin Medical University, Harbin, China.
Zhang Y; Department of Organic Chemistry, College of Pharmacy, Harbin Medical University, Harbin, China.

Cardiovasc Diabetol ; 22(1): 331, 2023 11 28.

Article en En | MEDLINE | ID: mdl-38017499

Asunto(s)

Transición Epitelial-Mesenquimal; Sirtuina 1; Humanos; Animales; Ratones; Sirtuina 1/metabolismo; Acetilación; Endotelio; Células Endoteliales de la Vena Umbilical Humana/metabolismo

Palabras clave

Deacetylation; Endothelialmesenchymal transition; Heart failure; SGLT-2 inhibitors; SIRT1

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Sirtuina 1 / Transición Epitelial-Mesenquimal Límite: Animals / Humans Idioma: En Revista: Cardiovasc Diabetol Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA / ENDOCRINOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: China

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