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Multisite Mpox Infection and Viral Dynamics Among Persons With HIV in Metro Atlanta.
Damhorst, Gregory L; Fujita, A Wendy; Fitts, Eric; Szabo, Brittany; Bowers, Heather B; Sabino, Courtney; Ahmed, Alaa; Wang, Ethan; Piantadosi, Anne; McLendon, Kaleb; Sullivan, Julie; Greenleaf, Morgan; McCaslin, Divine; Palmore, Melody; Anderson, Albert M; Aldred, Bruce; Gunthel, Clifford; Martin, Greg S; Colasanti, Jonathan A; Lam, Wilbur A; Bassit, Leda; Rao, Anuradha; Sheth, Anandi N; Titanji, Boghuma K.
Afiliación
  • Damhorst GL; Division of Infectious Diseases, Department of Medicine, Emory University.
  • Fujita AW; Ponce de Leon Center, Grady Health System.
  • Fitts E; Atlanta Center for Microsystems-Engineered Point-of-Care Technologies.
  • Szabo B; Division of Infectious Diseases, Department of Medicine, Emory University.
  • Bowers HB; Ponce de Leon Center, Grady Health System.
  • Sabino C; Atlanta Center for Microsystems-Engineered Point-of-Care Technologies.
  • Ahmed A; Department of Pathology and Laboratory Medicine.
  • Wang E; Division of Infectious Diseases, Department of Medicine, Emory University.
  • Piantadosi A; Ponce de Leon Center, Grady Health System.
  • McLendon K; Atlanta Center for Microsystems-Engineered Point-of-Care Technologies.
  • Sullivan J; Department of Pediatrics, School of Medicine.
  • Greenleaf M; Laboratory of Biochemical Pharmacology.
  • McCaslin D; Atlanta Center for Microsystems-Engineered Point-of-Care Technologies.
  • Palmore M; Department of Pediatrics, School of Medicine.
  • Anderson AM; Laboratory of Biochemical Pharmacology.
  • Aldred B; Emory Integrated Genomics Core.
  • Gunthel C; Department of Pathology and Laboratory Medicine.
  • Martin GS; Division of Infectious Diseases, Department of Medicine, Emory University.
  • Colasanti JA; Department of Pathology and Laboratory Medicine.
  • Lam WA; Department of Pathology and Laboratory Medicine.
  • Bassit L; Atlanta Center for Microsystems-Engineered Point-of-Care Technologies.
  • Rao A; Department of Pediatrics, School of Medicine.
  • Sheth AN; Atlanta Center for Microsystems-Engineered Point-of-Care Technologies.
  • Titanji BK; Ponce de Leon Center, Grady Health System.
J Infect Dis ; 229(Supplement_2): S213-S218, 2024 Mar 26.
Article en En | MEDLINE | ID: mdl-38019187
ABSTRACT
The 2022 mpox outbreak primarily involved sexual transmission among men who have sex with men and disproportionately affected persons with human immunodeficiency virus (HIV). We examined viral dynamics and clinical features in a cohort evaluated for mpox infection at a comprehensive HIV clinic in Atlanta, Georgia. Viral DNA was found in 8 oropharyngeal and 5 anorectal specimens among 10 mpox cases confirmed by lesion swab polymerase chain reaction. Within-participant anatomic site of lowest cycle threshold (Ct) value varied, and lower Ct values were found in oropharyngeal and anorectal swabs when corresponding symptoms were present. This provides insight into mpox infection across multiple anatomic sites among people with HIV.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Infecciones por VIH / Mpox / Minorías Sexuales y de Género Límite: Humans / Male Idioma: En Revista: J Infect Dis Año: 2024 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Infecciones por VIH / Mpox / Minorías Sexuales y de Género Límite: Humans / Male Idioma: En Revista: J Infect Dis Año: 2024 Tipo del documento: Article