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Perturbational phenotyping of human blood cells reveals genetically determined latent traits associated with subsets of common diseases.
Homilius, Max; Zhu, Wandi; Eddy, Samuel S; Thompson, Patrick C; Zheng, Huahua; Warren, Caleb N; Evans, Chiara G; Kim, David D; Xuan, Lucius L; Nsubuga, Cissy; Strecker, Zachary; Pettit, Christopher J; Cho, Jungwoo; Howie, Mikayla N; Thaler, Alexandra S; Wilson, Evan; Wollison, Bruce; Smith, Courtney; Nascimben, Julia B; Nascimben, Diana N; Lunati, Gabriella M; Folks, Hassan C; Cupelo, Matthew; Sridaran, Suriya; Rheinstein, Carolyn; McClennen, Taylor; Goto, Shinichi; Truslow, James G; Vandenwijngaert, Sara; MacRae, Calum A; Deo, Rahul C.
Afiliación
  • Homilius M; One Brave Idea and Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA. mhomilius@bwh.harvard.edu.
  • Zhu W; Harvard Medical School, Boston, MA, USA. mhomilius@bwh.harvard.edu.
  • Eddy SS; One Brave Idea and Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA. wzhu5@bwh.harvard.edu.
  • Thompson PC; Harvard Medical School, Boston, MA, USA. wzhu5@bwh.harvard.edu.
  • Zheng H; One Brave Idea and Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
  • Warren CN; One Brave Idea and Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
  • Evans CG; One Brave Idea and Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
  • Kim DD; One Brave Idea and Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
  • Xuan LL; One Brave Idea and Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
  • Nsubuga C; One Brave Idea and Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
  • Strecker Z; One Brave Idea and Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
  • Pettit CJ; One Brave Idea and Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
  • Cho J; One Brave Idea and Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
  • Howie MN; One Brave Idea and Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
  • Thaler AS; One Brave Idea and Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
  • Wilson E; One Brave Idea and Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
  • Wollison B; One Brave Idea and Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
  • Smith C; One Brave Idea and Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
  • Nascimben JB; One Brave Idea and Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
  • Nascimben DN; One Brave Idea and Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
  • Lunati GM; One Brave Idea and Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
  • Folks HC; One Brave Idea and Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
  • Cupelo M; One Brave Idea and Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
  • Sridaran S; One Brave Idea and Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
  • Rheinstein C; One Brave Idea and Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
  • McClennen T; One Brave Idea and Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
  • Goto S; One Brave Idea and Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
  • Truslow JG; One Brave Idea and Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
  • Vandenwijngaert S; One Brave Idea and Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
  • MacRae CA; Harvard Medical School, Boston, MA, USA.
  • Deo RC; One Brave Idea and Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Nat Genet ; 56(1): 37-50, 2024 Jan.
Article en En | MEDLINE | ID: mdl-38049662
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Diabetes Mellitus Tipo 2 Límite: Humans Idioma: En Revista: Nat Genet Asunto de la revista: GENETICA MEDICA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Diabetes Mellitus Tipo 2 Límite: Humans Idioma: En Revista: Nat Genet Asunto de la revista: GENETICA MEDICA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos