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Characterization of organic contaminants in hair for biomonitoring purposes.
Lallmahomed, Ashna; Mercier, Fabien; Costet, Nathalie; Fillol, Clémence; Bonvallot, Nathalie; Le Bot, Barbara.
Afiliación
  • Lallmahomed A; Univ Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR_S 1085, F-35000 Rennes, France.
  • Mercier F; Univ Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR_S 1085, F-35000 Rennes, France.
  • Costet N; Univ Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR_S 1085, F-35000 Rennes, France.
  • Fillol C; Direction of Environmental and Occupational Health, Santé publique France, Saint Maurice Cedex, France.
  • Bonvallot N; Univ Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR_S 1085, F-35000 Rennes, France.
  • Le Bot B; Univ Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR_S 1085, F-35000 Rennes, France. Electronic address: barbara.lebot@ehesp.fr.
Environ Int ; 183: 108419, 2024 Jan.
Article en En | MEDLINE | ID: mdl-38185045
ABSTRACT
Biological monitoring is one way to assess human exposure to contaminants. Blood and urine are often used as biological matrices, but hair is an innovative and effective tool for quantifying more biomarkers over a wider exposure window. In order to improve the use of hair in exposure assessment, this article identifies relevant compounds in the literature to investigate hair contamination. Statistical analysis was performed to correlate the physical-chemical properties of the relevant compounds and their concentration levels in hair. Phthalates, pyrethroids and organophosphate flame retardants were chosen for further study of the interpretation of hair measurements for exposure assessment. No significant correlation was found between the average concentration levels in the literature and the physical-chemical properties of the selected compounds. This work also explores the properties of hair and the analytical process that may impact the quantification of organic contaminants in hair. The sample preparation method (sampling, storage, washing) were also studied and adaptations were suggested to improve the existing methods.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Retardadores de Llama / Monitoreo Biológico Límite: Humans Idioma: En Revista: Environ Int Año: 2024 Tipo del documento: Article País de afiliación: Francia

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Retardadores de Llama / Monitoreo Biológico Límite: Humans Idioma: En Revista: Environ Int Año: 2024 Tipo del documento: Article País de afiliación: Francia