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The ADAM17 inhibitor ZLDI-8 sensitized hepatocellular carcinoma cells to sorafenib through Notch1-integrin ß-talk.
Xu, Chang; Gao, Xudong; Ren, Tianshu; Geng, Hefeng; Yang, Kaisi; Huang, Yaoguang; Zhang, Weige; Hou, Shanbo; Song, Aigang; Zhang, Yingshi; Zhao, Qingchun.
Afiliación
  • Xu C; Department of Clinical Pharmacy, Shenyang Pharmaceutical University, No. 103, Wenhua Road, Shenhe District, Shenyang 110016, China; Department of Pharmacy, General Hospital of Northern Theater Command, No. 83, Wenhua Road, Shenhe District, Shenyang 110016, China.
  • Gao X; Department of Pharmacy, General Hospital of Northern Theater Command, No. 83, Wenhua Road, Shenhe District, Shenyang 110016, China.
  • Ren T; Department of Pharmacy, General Hospital of Northern Theater Command, No. 83, Wenhua Road, Shenhe District, Shenyang 110016, China.
  • Geng H; Department of Clinical Pharmacy, Shenyang Pharmaceutical University, No. 103, Wenhua Road, Shenhe District, Shenyang 110016, China; Department of Pharmacy, General Hospital of Northern Theater Command, No. 83, Wenhua Road, Shenhe District, Shenyang 110016, China.
  • Yang K; Department of Clinical Pharmacy, Shenyang Pharmaceutical University, No. 103, Wenhua Road, Shenhe District, Shenyang 110016, China; Department of Pharmacy, General Hospital of Northern Theater Command, No. 83, Wenhua Road, Shenhe District, Shenyang 110016, China.
  • Huang Y; Department of Clinical Pharmacy, Shenyang Pharmaceutical University, No. 103, Wenhua Road, Shenhe District, Shenyang 110016, China.
  • Zhang W; Department of Clinical Pharmacy, Shenyang Pharmaceutical University, No. 103, Wenhua Road, Shenhe District, Shenyang 110016, China.
  • Hou S; Shandong Luoxin Pharmaceutical Group Stock Co., Ltd., No. 18, Huxi Rd., National New and High-tech Industrial Development Zone, Linyi, Shandong 276017, China.
  • Song A; Shandong Luoxin Pharmaceutical Group Stock Co., Ltd., No. 18, Huxi Rd., National New and High-tech Industrial Development Zone, Linyi, Shandong 276017, China.
  • Zhang Y; Department of Clinical Pharmacy, Shenyang Pharmaceutical University, No. 103, Wenhua Road, Shenhe District, Shenyang 110016, China; Department of Pharmacy, General Hospital of Northern Theater Command, No. 83, Wenhua Road, Shenhe District, Shenyang 110016, China. Electronic address: zhangyingshi526@
  • Zhao Q; Department of Clinical Pharmacy, Shenyang Pharmaceutical University, No. 103, Wenhua Road, Shenhe District, Shenyang 110016, China; Department of Pharmacy, General Hospital of Northern Theater Command, No. 83, Wenhua Road, Shenhe District, Shenyang 110016, China. Electronic address: zhaoqingchun1967
Pharmacol Res ; 203: 107142, 2024 May.
Article en En | MEDLINE | ID: mdl-38522759
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Carcinoma Hepatocelular / Receptor Notch1 / Proteína ADAM17 / Sorafenib / Neoplasias Hepáticas / Antineoplásicos Límite: Animals / Humans / Male Idioma: En Revista: Pharmacol Res Asunto de la revista: FARMACOLOGIA Año: 2024 Tipo del documento: Article
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Carcinoma Hepatocelular / Receptor Notch1 / Proteína ADAM17 / Sorafenib / Neoplasias Hepáticas / Antineoplásicos Límite: Animals / Humans / Male Idioma: En Revista: Pharmacol Res Asunto de la revista: FARMACOLOGIA Año: 2024 Tipo del documento: Article