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Oleanane-Type Triterpene Glycosides from Camellia phanii and Their α-Glucosidase Inhibitory Activity.
Lan, Hoang Thi Tuyet; Xuan, Vu Thi; Anh, Bui Thi Mai; Mai, Nguyen Thi; Dung, Nguyen Viet; Tai, Bui Huu; Hang, Nguyen Thi Minh; Thao, Vu Mai; Nhiem, Nguyen Xuan.
Afiliación
  • Lan HTT; University of Transport and Communications, 3 Caugiay, Dong Da, Hanoi, 11512, Vietnam.
  • Xuan VT; University of Transport and Communications, 3 Caugiay, Dong Da, Hanoi, 11512, Vietnam.
  • Anh BTM; University of Transport and Communications, 3 Caugiay, Dong Da, Hanoi, 11512, Vietnam.
  • Mai NT; University of Transport and Communications, 3 Caugiay, Dong Da, Hanoi, 11512, Vietnam.
  • Dung NV; Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Caugiay, Hanoi, 10072, Vietnam.
  • Tai BH; Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Caugiay, Hanoi, 10072, Vietnam.
  • Hang NTM; Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Caugiay, Hanoi, 10072, Vietnam.
  • Thao VM; Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Caugiay, Hanoi, 10072, Vietnam.
  • Nhiem NX; Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Caugiay, Hanoi, 10072, Vietnam.
Chem Biodivers ; 21(7): e202400053, 2024 Jul.
Article en En | MEDLINE | ID: mdl-38646830
ABSTRACT
Three new oleanane-type triterpene saponins, named camphanosides A-C (1-3), along with five known compounds, chikusetsusaponin IVa (4), spinasaponin A 28-O-glucoside (5), (-)-epicatechin (6), (-)-epicatechin 3-O-gallate (7), and (-)-epigallocatechin 3-O-gallate (8) were isolated from the leaves Camellia phanii Hakoda & Ninh. Their structures were established by 1D and 2D-NMR and mass spectral analysis and chemical methods. Moreover, compounds 1-5 were also evaluated for α-glucosidase inhibitory activity. Compounds 1-3 exhibited moderate α-glucosidase inhibitory activity with IC50 values of 230.7±18.0, 251.4±22.7, and 421.4±25.6 µM, respectively.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Ácido Oleanólico / Camellia / Alfa-Glucosidasas / Inhibidores de Glicósido Hidrolasas / Glicósidos Idioma: En Revista: Chem Biodivers Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2024 Tipo del documento: Article País de afiliación: Vietnam
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Ácido Oleanólico / Camellia / Alfa-Glucosidasas / Inhibidores de Glicósido Hidrolasas / Glicósidos Idioma: En Revista: Chem Biodivers Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2024 Tipo del documento: Article País de afiliación: Vietnam