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Vascular health of fathers with history of intracytoplasmic sperm injection.
Li, Pengzhu; Langer, Magdalena; Vilsmaier, Theresa; Kramer, Marie; Sciuk, Franziska; Kolbinger, Brenda; Jakob, André; Rogenhofer, Nina; Dalla-Pozza, Robert; Thaler, Christian; Haas, Nikolaus Alexander; Oberhoffer, Felix Sebastian.
Afiliación
  • Li P; Division of Pediatric Cardiology and Intensive Care, University Hospital, LMU Munich, Munich, Germany.
  • Langer M; Division of Pediatric Cardiology and Intensive Care, University Hospital, LMU Munich, Munich, Germany.
  • Vilsmaier T; Department of Gynecology and Obstetrics, Division of Gynecological Endocrinology and Reproductive Medicine, University Hospital, LMU Munich, Munich, Germany.
  • Kramer M; Division of Pediatric Cardiology and Intensive Care, University Hospital, LMU Munich, Munich, Germany.
  • Sciuk F; Division of Pediatric Cardiology and Intensive Care, University Hospital, LMU Munich, Munich, Germany.
  • Kolbinger B; Division of Pediatric Cardiology and Intensive Care, University Hospital, LMU Munich, Munich, Germany.
  • Jakob A; Department of Gynecology and Obstetrics, Division of Gynecological Endocrinology and Reproductive Medicine, University Hospital, LMU Munich, Munich, Germany.
  • Rogenhofer N; Division of Pediatric Cardiology and Intensive Care, University Hospital, LMU Munich, Munich, Germany.
  • Dalla-Pozza R; Department of Gynecology and Obstetrics, Division of Gynecological Endocrinology and Reproductive Medicine, University Hospital, LMU Munich, Munich, Germany.
  • Thaler C; Division of Pediatric Cardiology and Intensive Care, University Hospital, LMU Munich, Munich, Germany.
  • Haas NA; Department of Gynecology and Obstetrics, Division of Gynecological Endocrinology and Reproductive Medicine, University Hospital, LMU Munich, Munich, Germany.
  • Oberhoffer FS; Division of Pediatric Cardiology and Intensive Care, University Hospital, LMU Munich, Munich, Germany.
Aging Male ; 27(1): 2360529, 2024 Dec.
Article en En | MEDLINE | ID: mdl-38828619
ABSTRACT

OBJECTIVE:

Studies suggest that men who undergo assisted reproductive technologies (ART) may have a higher risk of cardiovascular disease; however, limited data on this matter is available. This observational pilot study aimed to investigate the overall vascular health of fathers with history of intracytoplasmic sperm injection (ICSI) compared to fathers whose partners conceived spontaneously.

METHODS:

Diet quality, physical activity, sedentary behavior as well as overall vascular function including the assessment of pulse wave analysis, intima-media thickness (cIMT), arterial stiffness of the common carotid artery (CCA) and blood lipids, were evaluated.

RESULTS:

A total of 34 fathers with history of ICSI and 29 controls (48.49 [46.32 - 57.09] years vs. 47.19 [40.62 - 55.18] years, p = 0.061) were included. After adjusting for age, no significantly increased cardiovascular risk was detected regarding vascular function.

CONCLUSIONS:

The results suggest an unaltered cardiovascular risk profile in fathers with history of ICSI. In the future, prospective multicenter studies are required to validate these preliminary results.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Enfermedades Cardiovasculares / Inyecciones de Esperma Intracitoplasmáticas / Padre / Grosor Intima-Media Carotídeo Límite: Adult / Humans / Male / Middle aged Idioma: En Revista: Aging Male Asunto de la revista: GERIATRIA Año: 2024 Tipo del documento: Article País de afiliación: Alemania

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Enfermedades Cardiovasculares / Inyecciones de Esperma Intracitoplasmáticas / Padre / Grosor Intima-Media Carotídeo Límite: Adult / Humans / Male / Middle aged Idioma: En Revista: Aging Male Asunto de la revista: GERIATRIA Año: 2024 Tipo del documento: Article País de afiliación: Alemania