Structures and Electron Transport Paths in the Four Families of Flavin-Based Electron Bifurcation Enzymes.
Subcell Biochem
; 104: 383-408, 2024.
Article
en En
| MEDLINE
| ID: mdl-38963493
ABSTRACT
Oxidoreductases facilitating electron transfer between molecules are pivotal in metabolic pathways. Flavin-based electron bifurcation (FBEB), a recently discovered energy coupling mechanism in oxidoreductases, enables the reversible division of electron pairs into two acceptors, bridging exergonic and otherwise unfeasible endergonic reactions. This chapter explores the four distinct FBEB complex families and highlights a decade of structural insights into FBEB complexes. In this chapter, we discuss the architecture, electron transfer routes, and conformational changes across all FBEB families, revealing the structural foundation that facilitate these remarkable functions.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Flavinas
Idioma:
En
Revista:
Sub-cellular biochemistry
/
Subcell Biochem
/
Subcell. biochem
Año:
2024
Tipo del documento:
Article
País de afiliación:
Estados Unidos