O-GlcNAc transferase congenital disorder of glycosylation (OGT-CDG): Potential mechanistic targets revealed by evaluating the OGT interactome.

Mayfield, Johnathan M; Hitefield, Naomi L; Czajewski, Ignacy; Vanhye, Lotte; Holden, Laura; Morava, Eva; van Aalten, Daan M F; Wells, Lance

Mayfield, Johnathan M; Hitefield, Naomi L; Czajewski, Ignacy; Vanhye, Lotte; Holden, Laura; Morava, Eva; van Aalten, Daan M F; Wells, Lance.

Afiliación

Mayfield JM; Department of Biochemistry and Molecular Biology, Complex Carbohydrate Research Center, University of Georgia, Athens, Georgia, USA.
Hitefield NL; Department of Biochemistry and Molecular Biology, Complex Carbohydrate Research Center, University of Georgia, Athens, Georgia, USA.
Czajewski I; School of Life Sciences, University of Dundee, Dundee, UK.
Vanhye L; Department of Clinical Genomics and Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
Holden L; Department of Biochemistry and Molecular Biology, Complex Carbohydrate Research Center, University of Georgia, Athens, Georgia, USA.
Morava E; Department of Clinical Genomics and Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
van Aalten DMF; School of Life Sciences, University of Dundee, Dundee, UK; Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark. Electronic address: daan@mbg.au.dk.
Wells L; Department of Biochemistry and Molecular Biology, Complex Carbohydrate Research Center, University of Georgia, Athens, Georgia, USA. Electronic address: lwells@ccrc.uga.edu.

J Biol Chem ; 300(9): 107599, 2024 Jul 24.

Article en En | MEDLINE | ID: mdl-39059494

Palabras clave

O-GlcNAc transferase (OGT); O-GlcNAcylation; O-linked N-acetylglucosamine (O-GlcNAc); histone modification; intellectual disability; neurodevelopment; post-translational modification (PTM); protein-protein interaction; transcription; transcription regulation

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: J Biol Chem Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos

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