Propoxyphene and acetaminophen. Possible effects on the fetus.
Clin Pediatr (Phila)
; 21(12): 752-4, 1982 Dec.
Article
en En
| MEDLINE
| ID: mdl-6890421
ABSTRACT
Propoxyphene (Darvon) and acetaminophen (Tylenol) are widely prescribed analgesic agents. Both can cross the placenta, and propoxyphene can produce serious withdrawal symptoms in newborns. Neither propoxyphene nor acetaminophen is considered a teratogen, yet, three malformed infants who were antenatally exposed to propoxyphene have previously been reported. We report a fourth case of an infant, with withdrawal symptoms and cranial-facial and digital malformations, born to a women who used propoxyphene and acetaminophen throughout her pregnancy. We suggest that possibility that the antepartum use of propoxyphene and acetaminophen, in combination, may be teratogenic.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Dextropropoxifeno
/
Síndrome de Abstinencia a Sustancias
/
Anomalías Inducidas por Medicamentos
/
Anomalías Múltiples
/
Acetaminofén
Límite:
Female
/
Humans
/
Male
/
Newborn
/
Pregnancy
Idioma:
En
Revista:
Clin Pediatr (Phila)
Año:
1982
Tipo del documento:
Article