Estimation of CHD risk in a French working population using a modified Framingham model. The PCV-METRA Group.
J Clin Epidemiol
; 47(12): 1353-64, 1994 Dec.
Article
en En
| MEDLINE
| ID: mdl-7730844
ABSTRACT
We adapt a recent model from the Framingham study (Circulation 1991; 83 356-362) to predict CHD in France for both sexes over a large age range. Calculations were based on data from the French PCV-METRA study. In France, the Paris Prospective Study model could predict CHD but only for men aged 43-53 years. Applied to men 43-53 years from the PCV-METRA, the Framingham model estimated a 5-year CHD risk (4%) lower than the risk reported in the Framingham sample, but significantly higher than the risk estimated by the French model (2%). Differences in estimated CHD risk between the Framingham and the PCV-METRA samples were explained for only 30% by adjustment on major CHD risk factors (mainly HDL-cholesterol and tobacco). Modifying the intercept in the Framingham model, agreement with estimated risk by the French model was improved from 29 to 80%. By an appropriate change of the intercept, the Framingham model might be used to estimate CHD risk in other populations.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Modelos Estadísticos
/
Enfermedad Coronaria
Tipo de estudio:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
País/Región como asunto:
Europa
Idioma:
En
Revista:
J Clin Epidemiol
Asunto de la revista:
EPIDEMIOLOGIA
Año:
1994
Tipo del documento:
Article
País de afiliación:
Francia